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headaches Clinical Trials

A listing of headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 216 clinical trials
H Heberto J Suarez-Roca, MD, PhD

Carotid Sinus Massage in Trendelenburg Position for Headache Relief

Headaches significantly impact patients' quality of life, with tension-type headaches and migraines being among the most prevalent types. There is growing evidence suggesting that blood pressure regulation and baroreceptor activity play a role in headache pathophysiology. Carotid sinus massage (CSM), particularly when combined with the modified Trendelenburg position, may modulate …

16 years of age All Phase N/A
A Anna Anselmo, Study Principal Investigator

PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE

Headache, in its episodic and chronic forms, cannot be considered solely as an isolated neurological symptom, but as a complex condition of a bio-psycho-social nature. While in the episodic form the painful episodes occur intermittently and have a variable impact on daily life, in the chronic form the disease evolves …

18 - 60 years of age All Phase N/A
C Chumgyili Li

Investigating the Impact of Acupuncture on the Quality of Life of Primitive Headaches Patients

Primary headache is one of the most common neurological diseases in modern society, which seriously affects the patient's quality of life. Although the use of painkillers can alleviate primary headache symptoms, it may also cause drug dependence. Therefore, alternative therapies that do not rely on drugs have attracted increasing attention …

18 years of age All Phase N/A

Efficacy of Therapy With PRP Injections Versus HA in Patients With Advanced Grade of GONArthrosis

Gonarthrosis is a chronic pathology affecting the knee joint and tissues. It is characterized by progressive degeneration of articular cartilage, bone and surrounding structures. Diagnosis is based on clinical, biological and radiological criteria. When knee osteoarthritis becomes symptomatic, it leads to pain associated with stiffness and functional discomfort, impacting on …

18 years of age All Phase N/A
L Laleh Zarrinkoob, MD, PhD

Pathophysiological Mechanisms and Implication of Treatment in Postural Puncture Headache

To improve treatment for post dural puncture headache, its pathophysiology needs to be explored. Dural puncture alters CNS dynamics; using advanced MRI, we aim to investigate PDPHs pathophysiology explained by brain movement, cerebral blood flow, CSF dynamics and the effect of epidural blood patch.

20 - 40 years of age All Phase N/A
R Robin Khapung, MD

Effect of Altitude on Postdural Puncture Headache After Caesarean Delivery

The aim of this study is to examine the effects of altitude (high altitude versus low altitude) on incidence and severity of postural puncture headache (PDPH) following spinal anaesthesia for caesarean delivery. The investigators hypothesized that the risk of PDPH would be higher in highlander parturients than in lowlander parturients.

18 years of age Female Phase N/A
G Ghulam Fatima, PhD*

Ischemic Compression Technique Versus Jones Technique in Cervicogenic Headache Patients

The primary objective of the study is to determine the effects of Jones and Ischemic compression technique on pain, range of motion and disability in patients with cervicogenic headache. Cervicogenic headache is a distinctive type of secondary headache where the pain originates from structures in the neck or cervical spine …

25 - 35 years of age All Phase N/A
M Muhammad Affan A Iqbal, MS-OMPT*

Suboccipital Muscle Inhibition Technique vs Rocabado Exercises on Cervicogenic Headache

The purpose of the study is to explore the effectiveness of Suboccipital muscle inhibition technique vs Rocabado exercises on cervicogenic headache. A randomized control trial was conducted at National Institute of Rehabilitation Medicine, Alees Medical Centre Islamabad. The sample size was 40 calculated through G-power 3.1. The participants were divided …

20 - 50 years of age All Phase N/A
X Xinkun Liu

Efficacy and Central Mechanisms of Electroacupuncture for Medication Overuse Headache

Acupuncture is commonly used for the prevention of migraine and tension-type headaches, and has been found to be effective in reducing both the frequency and severity of these conditions. However, studies on acupuncture for medication overuse headache (MOH) are limited, and current research has not been able to determine whether …

18 - 80 years of age All Phase N/A

Effectiveness of Third Occipital Nerve Pulsed Radiofrequency in Cervicogenic Headache

Cervicogenic headache is a secondary headache disorder originating from cervical spine structures and is frequently associated with chronic pain, functional limitation, and impaired quality of life. The third occipital nerve, which innervates the C2-3 zygapophyseal joint, plays an important role in the pathophysiology of cervicogenic headache. Pulsed radiofrequency is a …

18 years of age All Phase N/A

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