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headaches Clinical Trials

A listing of headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 216 clinical trials
Y Yu Fu

Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale

To establish a headache center in China that combines clinical, imaging and laboratory examinations, explore the feasible treatment options for migraine combined with patent foramen ovale, and search for the possible influencing factors, construct models that influence prognosis.

years of age All Phase N/A
T Tong Liu

Effects of PFO Closure on Glymphatic Function and Clinical Symptoms in Patients With Migraine

Patent Foramen Ovale (PFO) is a common congenital heart defect. Recent studies have suggested a potential association between PFO and migraines, particularly migraine with aura. It is hypothesized that PFO may allow microemboli or vasoactive substances from venous blood to bypass pulmonary metabolism and enter the arterial system directly, potentially …

18 - 60 years of age All Phase N/A
M Matias Costa

Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage

The goal of this clinical trial is to learn if an infusion of lidocaine, with or without steroids, into the middle meningeal artery (MMA) helps relieve severe headaches in patients with spontaneous subarachnoid hemorrhage (SAH). It will also study the safety of this treatment.

18 - 100 years of age All Phase 2
C Catello Vollono, MD

Vortioxetine in Depression and Concomitant Migraine

Depression and migraine are among the most prevalent conditions in the general population, and many research shows they are closely related. Migraine is one of the most common debilitating diseases, affecting over one billion people worldwide. Migraine is frequently comorbid with psychiatric conditions such as anxiety disorders and major depression, …

18 years of age All Phase N/A
I Iris Fernández Lázaro

Migraine Attack Pain Phase Prediction Study

The study of the ability to predict pain in a migraine attack, through premonitory symptoms and through an ambulatory monitoring device through real-time recording of hemodynamic variables, is one of the strategic lines of research of the unit. of Headaches at the Hospital de La Princesa since 2013 together with …

18 - 65 years of age All Phase N/A
A Ananya Tripathi, MS

Efficacy of Xeomin for Migraines in Patients With Traumatic Brain Injuries vs. Anomalous Health Incidents

This cohort study aims to compare the efficacy of Xeomin injections for migraine management in patients with a history of Traumatic Brain Injury (TBI) versus those with a history of Anomalous Health Incidents (AHI). The study will be conducted at the National Intrepid Center of Excellence (NICOE) in Bethesda, MD. …

18 years of age All Phase N/A

Acceptance and Commitment Therapy-based Rehabilitation of Post-concussion Symptoms

The investigators aim to evaluate effects of an outpatient rehabilitation program based on Acceptance and Commitment Therapy compared to usual care on function in patients with post-concussion syndrome (PCS) and post-traumatic headache (PTH). This study builds on the investigators' previous observational studies and treatment studies in this patient group.

18 - 65 years of age All Phase N/A
R Roberto De Icco, MD

Gepant treAtments: EffectIveNess and tolERability (GAINER)

The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of rimegepant as acute migraine treatment in a cohort of episodic or chronic migraine patients.

18 years of age All Phase N/A
R Roberto De Icco, MD

RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment

The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of rimegepant as preventive migraine treatment in a cohort of episodic or chronic migraine patients.

18 years of age All Phase N/A
A Aynur Parlatır, Supervizor

THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES

This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses. The study, which was conducted in a single-group prospective quasi-experimental design, was completed with 38 nurses in the operating theatre unit of a state …

18 years of age All Phase N/A

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