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Constipation Clinical Trials

A listing of Constipation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 89 clinical trials
C Chief, Functional Gastrointestinal Surgery

Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics

This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT). FMT is a procedure that transfers gut bacteria from healthy donors to patients to restore a balanced gut microbiome. The study will follow approximately 4,000 patients who have received or will …

3 years of age All Phase N/A
L Litao JIA, Doctor of Medicine

A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Symptoms

The goal of this observational study is to evaluate if Danning Tablets are effective in alleviating dyspepsia in patients with any of the following digestive symptoms: upper abdominal pain, bloating, loss of appetite, acid reflux or constipation. The main questions it aims to answer are: How effective are Danning Tablets …

18 - 75 years of age All Phase N/A
K Kara Murphy

Indiana University Gastrointestinal Motility Diagnosis Registry

Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions. It will also help in promoting future research in gastroenterology motility disorders

years of age All Phase N/A
s serhad bekir sünbül

Investigation of the Effect of Manual Therapy and Pelvic Floor Exercises on Pelvic Floor Muscles

The goal of this clinical trial is to Investigation of the effect of manual therapy and pelvic floor exercises on pelvic floor muscle in women with constipation. The main question\[s\] it aims to answer are: In addition to pelvic floor exercises, manual therapy applied to the pelvic floor muscles has …

18 - 55 years of age Female Phase N/A
R Ravinder K Mittal, MD

Defecation Patterns in Constipated Patients

Chronic constipation (CC) is a common condition that affects up to 25% of the population in North America. It poses a major burden on the healthcare cost. The pathophysiology of this condition is poorly understood and consequently there are inadequate treatments. Current diagnostic tests provide incomplete and often conflicting information. …

21 - 75 years of age All Phase N/A
S Stefano Nobile, MD, PhD, MSc

Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.

The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first 2 years of life. The main questions it aims to answer are: evaluate the prevalence of …

3 - 24 years of age All Phase N/A
Y Yaowen Hu

Effects of Lactulose on Gut Microbiota and Metabolism in Diabetic Constipated Patients

Constipation is the most common gastrointestinal manifestation in diabetic patients. Emerging evidence suggests that gut microbiota dysbiosis may contribute to the pathogenesis of diabetes, highlighting the need to investigate its role in diabetic constipation, though current research remains limited. Current management of diabetic constipation primarily relies on bulk-forming and osmotic …

18 - 70 years of age All Phase N/A
C Chin-Lin Hsu, Professor

Effects of Probiotics on Symptoms of Constipation in Adults With Functional Constipation

The purpose of this study was to evaluate the efficacy of 1 capsules of ABKefir per day on symptoms of constipation in subjects with functional constipation by clinical trial.

18 - 75 years of age All Phase N/A
H Harichandana Punukula, PharmD, MS

Tenapanor in Synucleinopathy-Related Constipation

Investigation of tenapanor as a potential treatment for synucleinopathy-associated constipation

50 - 89 years of age All Phase 2
A Asmaa Abdelnaby, Master

Anorectal Manometery in Pediatric Chronic Refractory Constipation

Anorectal manometry and high-resolution anorectal manometry (HRAM) are becoming the investigation of choice for understanding the pathophysiology of chronic constipation with or without fecal incontenance in children in many institutions. In high resolution anorectal manometery we are able to gain information whether the symptoms are related to sphincter dysfunction, impaired …

4 - 16 years of age All Phase 1/2

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