Advanced Filters
noise

Scar Tissue Clinical Trials

A listing of Scar Tissue medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 107 clinical trials
H Henry Huang, MD

Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy

Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in real time and ensuring an effective transmural lesion, different surrogate measures of lesion quality have been used. The Ablation Index (AI) is a …

18 years of age All Phase N/A
J Jun Yan, M.D.,Ph.D

Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy

Currently, low concordance (36%) is found between clinical complete response and pathologic complete response in patients with rectal cancer after neoadjuvant chemoradiotherapy. Probe-based confocal laser endoscopy (pCLE) provides a promising targeted optical biopsy to evaluate the response to neoadjuvant chemoradiotherapy. The aim of this study is to investigate whether pCLE-targeted …

18 - 80 years of age All Phase N/A
L Ljubinka Počrvina, Head of project-research and quality office

Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings

Burns are among the most common types of trauma worldwide, ranking fourth after traffic accidents, falls, and violence, and account for an estimated 265,000 deaths annually (WHO). Most burn injuries result from heat exposure, though other causes include friction, chemicals, and electricity. Effective burn treatment aims to promote wound healing …

6 - 17 years of age All Phase N/A
Y Yu-Chi Liu, MD, MCI, PhD

Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema

This observational study aims to validate the use of THz scanning system in corneal edema and corneal scars, and to investigate the accuracy and performance on the use of THz scanning system in the evaluation of the progression of corneal edema and corneal scars. Participants corneal scars and corneal edema …

21 years of age All Phase N/A
A Ahmed M Fahmy, Msc

Comparison Between Surgical Excision and Ultrasound Guided Evacuation in Management of Cesarean Section Scar Pregnancy.

patients diagnosed with cesarean section scar ectopic pregnancy type II will be divided into two groups, one will undergo surgical excision and the other one will undergo ultrasound-guided evacuation in order to compare safety and efficacy of both techniques.

18 - 45 years of age Female Phase N/A
M Mathias Willaert, MD

The Effectiveness of Hydroxychloroquine Versus Methotrexate in the Treatment of Lichen Planopilaris in Routine Clinical Care: a Patient Preference Trial

Rationale Lichen planopilaris (LPP) is a prevalent form of cicatricial alopecia, predominantly affecting women and causing irreversible hair loss. Hydroxychloroquine (HCQ) and methotrexate (MTX) are the most frequently used systemics for treatment of LPP in daily practice. Due to the absence of well-established treatment guidelines, this study aims to evaluate …

18 - 80 years of age All Phase N/A

Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars

This randomized, double-blind controlled study aims to compare the effect on appearance of post- surgical scars between daily application of siSPARC microneedle patch versus siSPARC + siLR4A microneedle patches. These are patches comprising short microneedles embedded with hydrolysed RNA (siRNAs).

21 - 75 years of age All Phase 2
A Anne Rollin, MD

Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone with the NOGA System

Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters. However, no study has investigated whether these electrical changes are associated with mechanical changes in local contractility. However, the voltage is closely correlated to …

18 - 85 years of age All Phase N/A
M Michael Prof. Dr. med. Soyka

Measuring the Volumes of Hypertrophic Scars and Keloids, Two Specific Kind of Scars, Over Different Points in Time in Patients Who Have Undergone Surgery and Evaluate 3D-cameras As a Possible Measuring and Documenting Tool Including Volumetry

Measuring the volumes of hypertrophic scars and keloids, two specific kind of scars, over different points in time in patients who have undergone surgery and evaluate 3D-cameras as a possible measuring and documenting tool including volumetry.

18 years of age All Phase N/A

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars

This study will enroll subjects with recently formed corneal scars that resulted from a corneal insult presenting and diagnosed within the past approximately 30 days and not less than approximately 7 days. All subjects will be assigned to CSB-001 investigational treatment on Day 1. All subjects will dose with CSB-001 …

18 - 80 years of age All Phase 1

Simplify language using AI