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Scar Tissue Clinical Trials

A listing of Scar Tissue medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 107 clinical trials

Genetic Analysis of Keloids

Keloids have a strong genetic component. The goal of this study is to identify genes and regulatory elements on chromosomes that are the cause for keloids or contribute to keloid scarring.

years of age All Phase N/A
D Delphine Legoupil, MD

Generation of an Artificial Intelligence Algorithm Based on the Analysis of Melanoma Peri-scar Dermatoheliosis, as a Predictive Factor of Response to Anti-PD-1

In the last decade, the advent of immunotherapies with inhibitors of immune checkpoints, such as anti-PD-1 and anti-CTLA-4, has revolutionized the treatment of advanced or metastatic melanoma. However, the clinical benefit remains limited to a subset of patients. Identifying the patients most likely to benefit from these novel therapies (and …

18 years of age All Phase N/A
R Renata D. Lemos, MD, MMed

Use of Botulinum Toxin A in Direct Eyebrow Lift Scar

Prospective, controlled and randomized study in which participants indicated for surgery to direct eyebrow lift will be randomized into two groups. In addition to surgery, the patients will be treated with botulinum toxin in one eyebrow and saline (placebo) in the other site. The patients participate as treatment and placebo …

18 years of age All Phase 2
J John Robb

Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp

Oftentimes, following surgery on the scalp, wounds are left to heal by themselves. This is called "second intention." Open wounds left to heal on the scalp often take 8 weeks or more to completely heal. The investigators are investigating how second intention closure compares to another established reconstruction technique, called …

18 years of age All Phase N/A
J John Robb

Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds

When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring. Several studies have been done to test ways to close wounds that reduce scarring. The most …

18 years of age All Phase N/A
J John Robb

Aesthetic Outcome of Tie-over Bolster Application in Surgical Wounds

When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring. Several studies have been done to test ways to close wounds that reduce scarring. One idea …

18 years of age All Phase N/A
D Daniel Eisen, MD

Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure

The purpose of this study is to determine whether intra-dermal versus transcutaneous purse-string closures have similar scar cosmesis and post-operative complications. The investigators will use a split wound model, where half of the wound will be closed with intra-dermal purse-string sutures and the other half will be closed with a …

18 years of age All Phase N/A
B Bonnie Carney, PhD

Treatment of Hypopigmented Scars With Bimatoprost

Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR). The treated scar will have bimatoprost delivered through the laser channels, while the control will have the …

18 years of age All Phase 2
A Abdulrahman Rageh

Combined Hystroscopic and Laparoscopic Repair of CS Scar Disorder

Combined hystroscopic and laparoscopic repair of symptomatic uterine Niche as new technique to maximize resolution of symptoms after niche repair with concomitant increase in RMT

20 - 45 years of age Female Phase N/A

Silicone Taping for the Improvement of Abdominal Donor Site Scars

This study will look at silicone tape compared to the current no dressing standard at the investigators institution, to determine if silicone tape provides a significant improvement in post-abdominoplasty scar appearance. Silicone tape will be added to half of the abdominoplasty incision of patients undergoing abdominally-based breast reconstruction procedures two …

18 - 65 years of age All Phase N/A

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