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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,855 clinical trials
N Nuccia Morici, MD

Cardiogenic Shock Integrated PHenotyping for Event Reduction

The purpose of this study is to better understand the time course of different biological mechanisms involved in acute decompensated heart failure complicated by cardiogenic shock throughout the evaluation of changes and the relationship among markers of inflammation (IL-6) and markers of increased endothelial permeability (Ang-2) or endothelial glycocalyx perturbation …

18 - 74 years of age All Phase N/A
I Ivar Sjaastad, MD, PhD

Investigating Myocardial Remodelling in the Failing Human Heart

Despite improvements in therapy, heart failure is a disease with high mortality and accelerating prevalence. To improve patient care, it is necessary to better understand the features and underlying mechanisms of myocardial remodeling; how it manifests in vivo and its underlying cellular and extracellular changes. The RELAX study will offer …

18 - 100 years of age All Phase N/A
P PAOLA VARLETA, MD

Gender Specific Registry in Subjects Hospitalized With Heart Failure in Santiago

This is an observational registry, which main purpose is to assess sex-related differences in heart failure (HF) presentation, management, and prognosis in patients admitted to a hospital with a certain diagnosis of HF. The diagnosis will be based on European Society of Cardiology (ESC) definition of HF ( clinical syndrome …

18 years of age All Phase N/A
M Mindy Thompson, MBA

Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients

The study aims to assess the effect of music on the heart resulting in a change in their exercise capacity among systolic heart failure patients undergoing Cardiopulmonary Exercise testing.

18 years of age All Phase N/A

HEMOTAG® Assessment for Short-term Outcomes of Heart Failure

Evaluation of the HEMOTAG® system in a less controlled environment and concurrently develop the system for use by patients with heart failure.

22 years of age All Phase N/A
E Elizabeth Medbury

Supporting Health in Veterans With Heart Failure

This study will test the effectiveness of a culturally-sensitive, telephone-based, tailored problem-solving intervention to improve physical and mental health in Veterans with heart failure (HF). Veterans will be recruited from VA clinics throughout the United States. As a component of this study, Veterans will partner with a registered nurse for …

18 years of age All Phase N/A

Ertugliflozin in Chronic Heart Failure

The purpose of this study is to determine the effects on heart failure signs and symptoms of the use of either ertugliflozin, metolazone or placebo, in conjunction with intravenous loop diuretic use in acute settings and chronic oral loop diuretic therapy. There are two general purposes for this study. The …

18 years of age All Phase 2
S Surita H Sidhu

3D Assessment of RV Function in Patients Undergoing LVAD Implantation

This goal of this study is to analyze images of the right ventricle taken via 3D transesophageal echocardiography (TEE) during left ventricular assist device (LVAD) implantation.

16 years of age All Phase N/A
N Nicolas GIRERD, MD,PhD

AMBulatory UltraSound for Heart Failure Management

AMBUSH study is a multicenter randomized, controlled, open-label clinical trial (PROBE (Prospective Randomized Open Blinded End-point) type). The main objective of AMBUSH study is to assess the effect of therapeutic management guided by pulmonary ultrasound and the assessment of the inferior vena cava in patients with heart failure seen in …

18 years of age All Phase N/A

V-Lap System For Wirelessly Measuring And Monitoring Left Atrial Pressure (LAP) In Patients With Advance Chronic Heart Failure

The objective of this study is to evaluate the safety and performance of the V-LAP System in subjects with New York Heart Association (NYHA) functional class II and III HF, irrespective of left ventricular ejection fraction.

22 - 88 years of age All Phase N/A

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