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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,881 clinical trials
P Peter Veldhuis, MD

Feasibility of TEE During Cardiac Arrest in Dutch Emergency Departments

The goal of this feasibility study is to learn if Dutch ED providers are able to use transesophageal echocardiography during cardiac arrest. The main question it aims to answer is: • are the ED providers able to determine the area of maximal compression of the heart using TEE

18 years of age All Phase N/A
C COO

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

The DART-HA study is a single-center, open label, trial intended to evaluate the clinical efficacy of standard treatment options for congestive heart failure (observation, diuretic or afterload reduction therapy) in patients without new symptoms who have developed abnormalities of the HeartLogic heart failure diagnostic feature.

19 years of age All Phase 4
C Cristina Rey-Reñones, PhD

Online Formation in Cardiopulmonary Resuscitation in a Rural Area.

Background: Sudden death due to cardiorespiratory arrest has a high mortality and in most cases occurs in out-of-hospital. Cardiopulmonary resuscitation (CPR) initiated immediately by witnesses doubles survival. However, rural areas present different challenges regarding the arrival of emergency services. As a result, the rural population could benefit from basic CPR …

18 years of age All Phase N/A
J John Granton, MD

Inhaled Nitric Oxide for Cardiac Arrest in Pediatrics and Adults (iNOCAPA)

This study is a multi-center, double blind, randomized controlled trial of inhaled nitric oxide (iNO) in children and adults with cardiac arrest (CA). The purpose of this pilot study is to test the feasibility of rapidly randomizing patients to iNO or sham treatment during cardiopulmonary resuscitation (CPR) or shortly after …

1 - 80 years of age All Phase 2
B Benjamin Tyrrell, MD

Doxycycline to Protect Heart Muscle After Heart Attacks

Current medical treatment allows more people to survive heart attacks than in the past. However, some of the survivors suffer heart disease and require hospitalization later on. The causes behind this heart disease (heart failure) after a heart attack are poorly understood. Matrix metalloproteinase 2 (MMP-2) is a protein that …

18 years of age All Phase 2

Clinical Study of Endocardial Myocardial Biopsy

In this study, patients with endocardial myocardial biopsy were selected to observe the safety of the operation, and pathological examination was performed. If necessary, special tests such as viral examination, mass spectrometry and molecular biology were performed to confirm the diagnosis, and follow-up was performed.

18 - 80 years of age All Phase 4
M MEHUL DHINOJA, FRCP

Stereotactic Ablative Radiotherapy for the Treatment of Refractory Ventricular Tachycardia

Ventricular tachycardia (VT) is an abnormal rhythm arising from the bottom chambers (ventricles) of the heart. The hearts of most patients who develop VT have been previously damaged by a myocardial infarction (heart attack) or other heart muscle diseases (cardiomyopathies). The damage produces scar or fatty deposits that conduct electrical …

18 - 85 years of age All Phase N/A

Mind Your Heart-II

This projects studies the role of mindfulness training (MT) to improve self-care among patients with heart failure and cognitive impairment.

18 years of age All Phase N/A

Effect of Resistance Training in Patients on the Waiting List for Heart Transplant

The present longitudinal, randomized, and blinded clinical trial aims to: Evaluate the effects of resistance training on the functional capacity, quality of life, and cardiac biomarkers of hospitalized patients with heart failure (HF) on the waiting list for heart transplantation (HTx). Evaluate the associations between Fried's frailty classification and functional …

18 - 70 years of age All Phase N/A

COgnitioN With VERiciGuat Evaluation in Heart Failure

CONVERGE-HF is a 4-center pilot phase IIb randomized control trial in ambulatory patients with chronic heart failure (≥ 6 months) and mild-to-moderate cognitive impairment.

18 years of age All Phase 2

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