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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,881 clinical trials
J Jiří Hynčica

Radiosurgery of Ganglion StELlatum In Patients With REFractory Angina Pectoris

The core hypothesis to be tested is that the radiosurgery of stellate ganglion (left one or both if left-sided without full relief of symptoms) is an effective therapy of refractory angina pectoris in patients with no other therapeutic options - proof of concept study.

18 years of age All Phase N/A
C COMISSÃO CIENTIFICA INCOR

Effect of Losartan on the Neurohumoral Axis and Ventricular Remodeling of Patients With Severe Aortic Regurgitation Undergoing Valve Surgery.

Why Is This Study Important? The heart has valves that help control blood flow. Aortic regurgitation (AR) is a condition where one of these valves (the aortic valve) doesn't close properly, causing blood to leak back into the heart. Over time, this makes the heart work harder and grow larger …

18 - 85 years of age All Phase 4
H Henning Bundgaard, PhD, DMSc

Accelerated Treatment of Endocarditis

Existing guidelines recommend a duration of antibiotic treatment of endocarditis of 4-6 weeks one or more types of intravenously administered antibiotics. The long hospitalization increases several risks for the patient, including mental strain and increased loss of function. Furthermore, it poses a significant financial burden on the health systems. Current …

18 years of age All Phase 4
D Doriane Richard, PhD

Interest of Parametric Positron Emission Imaging in the Diagnosis of Infections on Cardiac Valve Prosthesis

The objective of this study is to determine if early parametric positron emission computed tomography is useful to diagnose cardiac prosthetic valve infections.

18 years of age All Phase N/A
T Thomas Wasserscheid, MD

Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation

The aim of this study is to perform a pilot study investigating the first attempt intubation success rate differing between video laryngoscope nasotracheal intubation and direct laryngoscope nasotracheal intubation. The study population will consist of 60 neonates and infants with congenital heart disease less than 1 year of age who …

- 1 years of age All Phase N/A
J Jason Nall, PA-C

Stress and Congestive Heart Failure

The purpose of this study is to investigate whether acute stress can precipitate congestive heart failure (CHF) exacerbation in patients with CHF.

18 years of age All Phase N/A
Z Zoe Lincoln, MS

Fontan Fitness Trial

The goal of this randomized control trial is to learn about physical fitness and exercise habits in children aged 10-17 with the Fontan Circulation through a home-based, digital exercise intervention. The main questions it aims to answer are: Does a home-based, digital intervention increase physical activity (PA) in youth with …

10 - 17 years of age All Phase N/A

Peritoneal Ultrafiltration in Cardio Renal Syndrome.

Randomized, controlled, unblinded, adaptive design clinical trial to evaluate the safety and efficacy of PolyCore (Polydextrin, L-Carnitine, D-xylitol) peritoneal ultrafiltration (PUF) in patients with heart failure and reduced ejection fraction (HFrEF).

18 years of age All Phase 1/2
P Piers Barker, MD

Ventripoint Single Ventricle Study

This study will validate a coordinate-based 3-dimensional echocardiographic technique for the assessment of cardiac size and function in children and young adults with functional single ventricles.

years of age All Phase N/A
K Kathleen Ryan, MD

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

There are two primary goals of this multicenter clinical trial that combines an FDA device trial and a phase II drug trial in the same study cohort. These two goals are to: To evaluate the safety and effectiveness of the Cardiohelp Device for VA-ECMO (heart-lung support) for up to 30 …

- 16 years of age All Phase 2

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