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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,858 clinical trials

Cardiology Research Dubrava Prospective Registry

Cardiology Research Dubrava registry is a prospective, single centre registry including patients with acute coronary syndrome with and without ST segment elevation, patients with heart failure who were prescribed with SGLT-2 inhibitors, patients implanted with TAVI, patients with venous thromboembolism, patients with pulmonary embolism who underwent thromboaspiration procedure, patients implanted …

18 years of age All Phase N/A
R Richard Whitlock, MD PhD FRCSC

Surgical Ablation of AF Efficacy Trial

SAFE is an international multicentre RCT of concomitant surgical atrial fibrillation (AF) ablation in patients with paroxysmal or persistent AF undergoing cardiac surgery.

18 years of age All Phase N/A
B Barry Borlaug

Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume

The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular …

18 years of age All Phase N/A
T Tommaso Gori, Prof Dr, PhD

Mainz Intracoronary Database. The Coronary Slow-flow and Microvascular Diseases Registry

Primary goal of the registry is to collect prospective data on patients undergoing coronary angiography in Mainz. Following amendment of the procol, this study will also include patients who received an Aborb bioresorbable scaffold for the therapy of de novo stenoses.

years of age All Phase N/A
M Marc Bonaca, MD

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.

18 years of age All Phase 3
X Xiaohong Pan

Clinical Study of Impact of Different Pacing Site in Patients

At present, cardiac pacing has been widely used in the treatment of bradyarrhythmias and heart failure, which can effectively improve the survival rate of patients. With the rapid development of technology, different sites can be chosen to pace, such as right atrial appendage, the atrial septum and the right atrial …

18 - 100 years of age All Phase N/A
M Morten Lock Hansen, MD, PhD

Danish Evaluation of Early Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure

The DanAblate-HF trial will investigate whether early catheter ablation treatment for atrial fibrillation in patients with heart failure is superior to standard treatment.

18 - 80 years of age All Phase N/A
S Sara Ares Blanco, MD, PhD

Determining Efficacy of an Artificial Intelligence-based System for Heart Failure Detection Through Interpretation of Electrocardiograms (DECISION)

The DECISION trial aims to evaluate the efficacy of an artificial intelligence (AI)-powered system, Willem™, for improving the detection of heart failure (HF) in primary care settings by interpreting electrocardiograms (ECGs). The study seeks to answer whether AI-assisted ECG interpretation enhances diagnostic accuracy and clinical outcomes compared to standard ECG …

65 years of age All Phase N/A
R Rosemary Kennedy, PhD,RN,FAAN

The HEARTFELT Study

This pragmatic randomized crossover trial looks at the effect(s) of using a remote patient monitoring device (Heartfelt device) with health alerts to monitor the development of peripheral edema in patients with heart failure (HF). The hypothesis is that this passive measurement method will lead to better data availability, which in …

22 years of age All Phase N/A
O Oscar Braun, MD, PhD

Non-Invasive Hemodynamic Monitoring in Hospitalized Heart Failure

Heart failure hospitalization is associated with a high risk of early readmission and mortality. There is an unmet clinical need for low-burden, non-invasive methods to better understand congestion and hemodynamic status during hospitalization. This observational study evaluates the association between non-invasive measurements obtained with the Acorai Device 1.0 and clinical …

18 years of age All Phase N/A

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