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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,769 clinical trials
C Chan Joo Lee

Validation of the Prognostic Impact of a Retinal Photograph-based Cardiovascular Disease Risk Stratification System in de Novo HFrEF

"Despite significant advances in pharmacologic and device-based therapies, heart failure (HF) remains a major public health burden, with persistently high rates of hospitalization, impaired quality of life, and excess mortality-often exceeding those of leading malignancies. Prognosis in HF is shaped by its underlying etiology: ischemic HF often responds to revascularization …

20 years of age All Phase N/A
K Kate Dalton, MS, RD, CCRC

Impella Reverse Remodeling in End-Stage Heart Failure

This observational study is being done to learn more about heart attack recovery in patients supported with the Impella 5.5 left ventricular assist device (LVAD) as part of their standard of care. There are three stages in this study: screening, treatment and post treatment. There will be two phases of …

18 years of age All Phase N/A
A Andrzej Walczak, MD, PhD

Polish Transcatheter Transfemoral Mitral Valve-in-Valve Implantation (Mitral ViV) Registry

In recent years increasing number of mitral bioprosthesis implantation, especially in elderly population, is observed. Bioprosthetic valves are associated with a lower risk of thrombotic and bleeding adverse events compared with mechanical prostheses, but their use is limited due to their durability. After years numerous patients may develop bioprosthesis failure, …

18 years of age All Phase N/A

Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study

Evaluation of potential nerve damage after radial CAG/PCI.

18 years of age All Phase N/A
S Stylianos Daios, MD, MSc

Novel Echocardiographic Biomarkers Assessing the Myocardial Work in Heart Failure

This study seeks to investigate the clinical value of novel echocardiographic indices, including myocardial work parameters, during the acute phase of heart failure hospitalization. The trajectory of novel echocardiographic indices from the start to the end of hospitalization will be captured, as a means to unravel and subsequently better understand …

18 years of age All Phase N/A
M Miju Shin

Efficacy and Safety of Zotarolimus-eluting Stent Overexpansion With OCT

Investigators aimed to evaluate efficacy and safety of expansion capacity of zotarolimus-eluting Stent assessed by optical coherence tomography (OCT) in vivo study.

19 years of age All Phase N/A
W Weijing Wang, PhD

The Cerebral Microcirculation Diseases and Coronary Microcirculation Disease Study

Ischaemic heart disease (IHD) and degenerative brain disease are two major sources of death and disability affecting all countries. While the consequences of obstructive disease in major vessels supplying blood to both organs have been widely documented, less attention has been paid to disease processes affecting the microcirculation that may …

45 - 80 years of age All Phase N/A
K Ki Hong Choi, MD

Relationship Between Coronary Microvascular Dysfunction and Improvement of Left Ventricular Systolic Function in Patients With Heart Failure With Reduced Ejection Fraction Caused by Non-ischemic Etiology

This study aims to evaluate the incidence of coronary microvascular dysfunction (CMD) and its prognostic implication for the improvement of left ventricular function in patients who have been diagnosed with heart failure with reduced ejection fraction (HFrEF) caused by non-ischemic etiology.

19 years of age All Phase N/A
S Shoujun Li, MD

The Follow-up System of Pediatric Heart Failure and the Establishment of End-stage Heart Failure Registry

Establish a follow-up management system for pediatric heart failure and a registration platform for end-stage heart failure

- 14 years of age All Phase N/A
C Chenguang l, MD, PhD

µQFR for Branch Stenosis After Single Stent in Bifurcation Lesions

Murray-law based single-view quantitative flow ratio (µQFR) has been recommended for guiding percutaneous coronary intervention (PCI) in selective patients. However, it's reliability has not been validated in bifurcation lesions which present complex anatomy and flluid conditions before and after PCI. The goal of this study is to investigate the diagnostic …

18 years of age All Phase N/A

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