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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,908 clinical trials
J James Daubert, MD

PKP2-ACM Natural History Study

The goal of this study is to describe the natural history and clinical events for patients who have Arrhythmogenic Cardiomyopathy with Pathogenic Plakophilin-2 Variants (PKP2-ACM) managed with standard of care.

12 years of age All Phase N/A

Interest of the SPECT-CT Scan SUVspect in the New Generation of Gamma-cameras With Semiconductor

Since 2017, a revolution began in the departments of nuclear medicine, with the routine use of gamma-cameras with semiconductor. These gamma-cameras (which obtained the CE-marking in 2016), offer a technological breakthrough by providing an additional information. They allow "to quantify" for the 1st time in clinical routine conditions, the quantity …

18 years of age All Phase N/A
C Chiara Lanzani, MD

Multidisciplinary Dissection of Renal and Metabolic Effects of Glyfozines on Elderly Patients: From Molecular Aspects to Clinical Indications

The project aims to study the impact of SGLT2i therapy on clinical and biochemical aspects. in elderly. The project will combine different types of data, such as clinical and biological information, and will use advanced Bayesian statistical methods to understand the relationship between risk factors and patient outcomes following treatment …

65 years of age All Phase N/A
G Gozde Altun

Correlation of the EUROSCORE-II With POSPOM in Cardiac Surgery: A Single Center, Retrospective, Cross- Sectional Study

In cardiac surgery patients, due to the surgical burden combined with existing comorbidities, evaluating the preoperative clinical status of patients and predicting mortality rates has become an important issue of interest for clinicians. For this purpose, mortality has been predicted with various scoring systems. EUROSCORE is a scoring system used …

18 - 100 years of age All Phase N/A
B Barry Borlaug

Pulmonary Hypertension in Left Heart Disease

The goal is to compare patients with and without varying severity of pulmonary vascular disease based upon hemodynamic signatures, echocardiographic measures, and lung ultrasound, in tandem with expired gas metabolic testing and blood sampling.

18 years of age All Phase N/A
M Mylene Juneau, MN

Complete Lifestyle Medicine Intervention Program

This project will use a mixed design and will be conducted at the West Parry Sound Health Centre. Based on similar studies there is an expected 10% drop-out rate so 20 participants per group will be invited to aim to have 15 finish. Total participants invited over the two-year study …

18 years of age All Phase N/A
D Deborah Kwon, MD

Comparative Imaging Assessment of Valvular Heart Disease

The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.

18 - 90 years of age All Phase N/A
N Nana Theodorou

High Frame Rate Ultrasound in Heart Disease Assessment

The study will compare standard ultrasound images to high frame rate ultrasound images in patients with heart disease or with a low risk of heart disease to see if a higher frame rate of ultrasound adds to the information obtained from standard ultrasound.

18 years of age All Phase N/A
R Robin Le Ruz, MD

Pressure-Volume Loop Assessment in Valvular Heart Disease

The VHD PV loop study intends to assess invasive right ventricular to pulmonary artery (RV-PA) coupling in patients with valvular heart disease (VHD). Invasive RV-PA coupling is measured by using conductance catheters, the gold standard assessment for ventricular physiology. Several non-invasive parameters have been reported as surrogates for this complex …

18 years of age All Phase N/A

SNORD3A IN ISCHEMIC HEART DISEASE AND HEART FAILURE

This is a prospective, non-randomized, single center, open label clinical study enrolling patients affected by 1) chronic ischemic heart disease with evidence or suspect significant myocardial ischemia (group 1, CCS) or 2) acute coronary syndromes (group 2, ACS), both undergoing coronary angiography and eventually coronary revascularization at the Department of …

18 years of age All Phase N/A

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