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Wounds Clinical Trials

A listing of Wounds medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,036 clinical trials
M Michelle Barnes, BScPT

Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?

This proof-of-principle study will determine if breathing an increased concentration of oxygen above the concentration in normal room air results in changes in the sensory and motor function in people with subacute or chronic, severe spinal cord injury (SCI).

18 - 65 years of age All Phase 0
J Jill Wecht, EdD

Autonomic Effects of Stimulation in SCI

This study aims to determine the effects of transcutaneous spinal cord stimulation to increase blood pressure and use that device to increase power output and heart rate recovery during arm cycle ergometry. In addition, the investigators will see if the stimulation helps regulate body temperature when in a cool environment.

18 years of age All Phase N/A

Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury

The HemON study aims to evaluate the safety and preliminary efficacy of ARC-IM Therapy (Epidural Electrical Stimulation) to improve hemodynamic management and trunk control in people with sub-acute or chronic spinal cord injury (\>= 1 month post injury) between C3 and T6 inclusive, who suffer from orthostatic hypotension.

18 years of age All Phase N/A
E Elizabeth W Regan, DPT, PhD

Usability of the Adapted Rower for People With Spinal Cord Injury

The goal of this clinical trial is to examine usability of a locally built adaptive rower for people with spinal cord injury using an established and tested design. The main questions it aims to answer are: What exercise intensity of activity do users achieve on the rower for steady state …

18 years of age All Phase N/A
R Randy D Trumbower, PT, PhD

Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with chronic spinal cord injury (SCI). The goal of the study is to understand the mechanisms by which intermittent hypoxia enhances …

18 - 75 years of age All Phase N/A
S Soshi Samejima, DPT, MS

Transcutaneous Spinal Stimulation and Exercise for Locomotion

Growing evidence indicates that electrical spinal cord stimulation improves motor functions both immediately and over the long term via modulating the excitability of spinal circuitry in patients with spinal cord injury. Recently, a novel, non-invasive, well-tolerated, and painless lumbosacral transcutaneous electrical stimulation strategy was demonstrated to be effective in improving …

21 - 70 years of age All Phase N/A

Dosing of Overground Robotic Gait Training with Functional Outcomes and Neuroplasticity After Spinal Cord Injury

The DOOR SCI project examines dosing effects of robotic gait training (RGT) and transcranial magnetic stimulation (TMS) initiated during inpatient rehabilitation and continued through early outpatient rehabilitation

16 - 85 years of age All Phase N/A
I Ismael Seanez, PHD

Spinal Cord Stimulation and Training

This study will help the investigators better understand the changes in short-term excitability and long-term plasticity of corticospinal, reticulospinal and spinal neural circuits and how the changes impact the improvements of spinal cord stimulation (SCS) mediated motor function.

16 - 65 years of age All Phase N/A
A Ashraf S Gorgey, MPT,PhD, FACSM

Epidural Stimulation and Resistance Training After SCI

Spinal cord injury (SCI) is a devastating health problem for tens of thousands of military personnel, Veterans and civilians annually. Many persons with SCI must use a wheelchair for their entire life. A new scientific breakthrough called "lumbosacral epidural stimulation" or "ES" can help people with SCI to stand, step …

18 - 60 years of age All Phase 2/3
S Sheng-Tzung Tsai

Spinal Cord Stimulation for Spinal Cord Injury Patients - Regain Walk and Alleviate Pain

The study aims to examine the plausible interventional mechanisms underlying the effects of epidural spinal cord stimulation.

20 - 70 years of age All Phase N/A

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