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Wounds Clinical Trials

A listing of Wounds medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,971 clinical trials

Efficacy of a Photosynthetic Dermal Matrix for the Treatment of Full-Thickness Skin Wounds

The goal of this clinical trial is to evaluate whether the incorporation of photosynthetic microalgae into scaffolds for dermal regeneration improves healing outcomes in adult patients with acute and cronic full-thickness skin wounds. The primary objectives are to determine whether the use of photosynthetic scaffolds enhances wound granulation and reduces …

18 years of age All Phase 2
K Karin Hediger, Prof. Dr.

Animal-assisted Trauma-focused Therapy for Children and Adolescents

The study aims to investigate how the inclusion of an animal into a trauma-focused group therapy program (TF-CBT) affects therapy motivation of children and adolescents suffering from post-traumatic stress. 80 children and adolescents aged 9 to 17 years are recruited for the study. Participants must have experienced at least one …

9 - 17 years of age All Phase N/A
V Vincent P Duron, MD

Effect of Giving Reduced Fluid in Children After Trauma

This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volumes of IV fluid. …

6 - 15 years of age All Phase N/A
E Eduard Shaykhinurov

Single Shot Exparel vs Catheters in Lower Extremity Trauma

This study will compare the use of single-shot Exparel, a long-acting local anesthestic, with the use of catheters that deliver a continuous flow of the short-acting local anesthetic ropivacaine. The comparison will be done in patients who receive preoperative adductor and sciatic nerve blocks prior to orthopedic surgery for traumatic …

18 years of age All Phase 4

EIT-Guided PEEP Optimization in Trauma and Postoperative ARDS

Acute respiratory distress syndrome (ARDS) remains a serious and often fatal complication in patients following severe trauma or major surgery. Mechanical ventilation is essential for supportive care in this population, but may aggravate lung injury when suboptimal ventilatory settings are applied. Positive end-expiratory pressure (PEEP) is crucial for maintaining alveolar …

18 - 90 years of age All Phase N/A
M Michelle L. Miller, PhD

The New Empowerment After eXposure to Trauma (NEXT) Study

The NEXT Study is a randomized controlled pilot examining the feasibility and acceptability of a revised perinatal PTSD protocol. This study will randomize perinatal participants with PTSD to receive NET (n=45); treatment group) and will be compared to perinatal women randomized to usual care (n=45; comparator group). The overall objective …

18 - 50 years of age Female Phase N/A
N Nina Mørkved, Assoc. Professor

The Key to Integrated Trauma Treatment in Psychosis Trial

Schizophrenia spectrum disorders (SSDs) have a significant trauma etiology: trauma has been reported in 65 - 80% in this patient group and have a negative impact on prognosis. Trauma treatment is currently not offered in SSDs due to a lack of evidence. KIT is a pragmatic trial comparing the effectiveness …

16 years of age All Phase N/A
B Betty Henderson-Matthews, MA

Trauma and Cardiometabolic Health in an American Indian Community

Volunteers for the study are asked to participate in two laboratory sessions. In the first laboratory session, volunteers are asked to provide a blood sample which will be used to measure factors related to health. Participants also complete questionnaires related to demographic and health-related information and undergo evaluations of their …

18 - 40 years of age All Phase N/A
E Erica, MPH

Identifying and Treating Depression in the Orthopaedic Trauma Population

The goal of this trial is to pilot a way for orthopaedic surgeons to safely screen for depression and provide treatment for depression with medication. The main questions it aims to answer are: What are the outcomes of patients who screen positive for depressive symptoms and are prescribed either an …

18 years of age All Phase 4

Continuous Passive Motion Versus Heterotopic Ossification

The investigators hypothesize that Heterotopic Ossification (HO) formation can be suppressed if the application of a Continuous Passive Motion (CPM) device can be performed for a substantial amount of time. The investigators will use the following study design: a pilot study with 10 ICU patients receiving CPM and 10 matched …

15 - 70 years of age All Phase N/A

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