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Wounds Clinical Trials

A listing of Wounds medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,942 clinical trials
T Timothy C Mauntel

Pre- and Post-neuromusculoskeletal Injury Risk Evaluation for Return-to-Duty Enhancement

The purpose of this study is to develop comprehensive and efficient pre- and post- musculoskeletal injury (MSKI) risk assessments for Service members, incorporating both objective and subjective measures. This is a multi-site observational study to identify the pre- and post-MSKI physical and psychosocial factors contributing to MSKI risks and undesired …

18 - 44 years of age All Phase N/A

Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II

The study intervention focuses on exploring the use of angiotensin II as a primary vasopressor compared to norepinephrine in cardiac surgery patients to investigate whether angiotensin II can reduce the occurrence of moderate/severe acute kidney injury (AKI). Despite its potential, as suggested by trials involving surgical patients, there is currently …

18 years of age All Phase 3
T Tuo Pan, MD

Effect of Colchicine on Perioperative Anti-inflammatory Organ Injury in Cardiac Surgery

All patients will be completed collection of demographic data, clinical data, and be observed for inflammatory organ damage, oxygenation index or SpO2/ FIO2, WBC, NEU, interleukin-1β, interleukin-6, interleukin-8 (IL-1β/6/8), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), procalcitonin (PCT), myoglobin (Myo), creatine kinase-MB (CK-MB), high-sensitivity cardiac troponin T (hs-cTnT), neutrophil elastase …

50 - 80 years of age All Phase 3
Q Qiongfang Wu, MD

Goal-directed Hemodynamic Management and Kidney Injury After Radical Nephrectomy or Nephroureterectomy

Radical nephrectomy and nephroureterectomy are common operations for the treatment of renal cell carcinoma and upper tract urothelial carcinoma, respectively. However, acute kidney injury frequently occurs after surgery. And the occurrence of acute kidney injury is associated with an increased risk of chronic kidney disease. Intraoperative hypotension is identified as …

18 years of age All Phase N/A
E Emily Sweeney, MD

Quality of Life and Life Satisfaction in Pediatric and Adolescent Gymnasts Through Injury

This study aims to assess the quality and life and life satisfaction of pediatric and adolescent gymnasts throughout their musculoskeletal injury recovery.

8 - 18 years of age All Phase N/A
L Li Huang, MD, PhD

Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery

Acute renal injury (AKI) is a common complication after cardiac surgery and is associated with worse outcomes. It is now realized that intraoperative hypotension is an important risk factor for the development of AKI. In a recent randomized controlled trial of patients undergoing major noncardiac surgery, intraoperative individualized blood-pressure management …

50 years of age All Phase N/A

A Prospective Cohort Study on Drug-induced Liver Injury in China(DILI-P)

This is a multi-center, prospective, non-interventional cohort study . Its primary objectives are: assess DILI patients' clinical characteristics, disease progression and influencing factors in clinical practice; learn about suspected drug caused DILI,rechallenging, liver biochemical abnormalities mode, etc.

years of age All Phase N/A
J Jason Sperry, MD

Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial

The Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) trial will be a 5-year (3-year enrollment), open label, phase-3, multi-center, early in-hospital phase randomized trial utilizing burn centers from within the LITES network and will enroll approximately 750 injured adult patients who have suffered large 2nd …

18 - 75 years of age All Phase 3

Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney Injury

The study investigates whether sodium bicarbonate is able to reduce the occurrence of major adverse kidney events on day 90 (MAKE90) in critically ill patients with metabolic acidosis and acute kidney injury (AKI). While its efficacy in this context has been suggested in a subgroup analysis of the BICAR-ICU trial …

18 years of age All Phase 4

Brain-injured Patients Extubation Readiness Study

The BIPER study is a stepped wedge cluster randomised clinical trial aiming to decrease extubation failure in critically-ill brain-injured patients with residual impaired consciousness using a simple clinical score.

18 - 75 years of age All Phase N/A

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