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Wounds Clinical Trials

A listing of Wounds medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,942 clinical trials
Y Yan Liu

Phase II Clinical Trial of KJ101in the Treatment of Deep II Degree Burns

This multicentre, randomised, double-blind, dose-finding, active- and placebo-controlled Phase II clinical trial will evaluate the safety, efficacy, pharmacokinetic profile, and immunogenicity of KJ101 for the debridement of deep second-degree burns. The trial will provide supporting evidence for subsequent Phase III trials.

18 - 65 years of age All Phase 2
E Emmanuel Dudoignon

Determining Elements of Anti-Fungal Immunity in BURN Patients

Scientific justification Invasive fungal diseases (IFDs) pose a substantial threat, especially in immunocompromised patients, necessitating urgent research focus and therapeutic advancements. The IFI-BURN study, involving a cohort of patients with severe burn injury (n=276), revealed a significant IFD incidence of 31.6% and underscored their critical impact on morbidity and mortality. …

18 years of age All Phase N/A
N Nesma M Allam, PhD

Impact of Inspiratory Muscle Training Post-Burn

Pulmonary dysfunction can be developed as a result of complications caused by direct thermal injury to the respiratory tract, smoke irritations, and respiratory tract infection. Although the survival rates of patients with burn injury have increased because of improved acute management, pulmonary complications have continued to be the main cause …

20 - 50 years of age All Phase N/A
J Janni K Thillemann, Dr

Danish Multicenter Scapholunate Ligament Study

Comparison of two surgical techniques commonly used for reconstruction of the scapholunate (SL) ligament. A randomized multicenter study.

18 - 60 years of age All Phase N/A

Use of an Integrated Orthotic and Rehabilitation Initiative for Treatment of Lower Extremity Musculoskeletal Disorders

The Intrepid Dynamic Exoskeletal Orthosis (IDEO) is a custom, energy storage and return ankle orthosis proven to improve functional ability when coupled with a customized high-intensity rehabilitation program. The Return to Performance (RTP) clinical pathway is the civilian version of the evidence-based Return To Run (RTR) clinical pathway. Together, the …

18 years of age All Phase N/A
M Mark Donald White, M.D., F.A.C.S.

Indigotindisulfonate Sodium as an Aid in Determination of Ureteral Patency in Patient's With Renal Impairment

This is an open label, randomized, multicenter study to evaluate the efficacy and safety of two dose levels (2.5 mL and 5.0 mL) of Indigotindisulfonate Sodium Injection, USP 0.8% when used as an aid in the determination of ureteral patency in patients with different degrees of renal impairment.

18 - 85 years of age All Phase 4
C Cyril Dufourcq

Does Performing a Composite Test 3 Months Post-operatively Reduce the Risk of Failure to Return to Sport After Lateral Ankle Ligamentoplasty?

Ankle sprain is one of the most common pathologies in the general population (between 2.1 and 3.2 per 1000 patients per year). Nearly 40% of patients will develop chronic instability in the year following the sprain. We also know that a premature return to sport is a risk factor for …

18 - 50 years of age All Phase N/A
O Oğuz Önalan

Kinesio Taping Effects on Balance and Ankle Proprioception

Ankle injuries are among the most common musculoskeletal injuries, affecting both athletes and the general population. Various methods are used to prevent such injuries, but the effectiveness of different kinesio taping applications on joint position sense and balance remains unclear. This study aims to investigate the effects of different kinesio …

18 - 25 years of age All Phase N/A
R Ronald A. Lehman, MD

Tranexamic Acid to Reduce Blood Loss in Spine Surgery

This study is designed to evaluate the efficacy of topical tranexamic acid to reduce perioperative blood loss, reduction in postoperative drain output and allogenic transfusion requirements. The proposed study will be a prospective, randomized, double-blind (subject, surgeons, investigators, research coordinators) placebo-controlled study. Patients requiring posterior spinal fusion will be enrolled …

18 - 80 years of age All Phase 2/3

Self-locking Tenodesis of the Long Chief of the Biceps Vs. Lasso 360 Tenodesis in Arthroscopic Rotator Cuff Repair Rotator Cuff Repair

The aim of this study is to compare the clinical results and complications of self-locking biceps tenodesis and double 360 lasso loop biceps tenodesis for the treatment of long chief of biceps or superior labrum anterior-posterior (SLAP) tendon pathology during shoulder arthroscopy in patients undergoing arthroscopic rotator cuff repair. Currently, …

40 years of age All Phase N/A

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