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Bipolar Disorder Clinical Trials

A listing of Bipolar Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 166 clinical trials
W Weihua Yue

Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study

The project proposes to develop a digital product based on cognitive behavioral therapy for the assisted treatment of depression. The digital cognitive behavioral therapy in this study is conducted based on a self-developed mobile applet. The therapy is developed by psychotherapists, which is conducted for a total of 8 weeks, …

14 - 60 years of age All Phase N/A
K Karin Huizer, PhD

Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderS

The goal of this clinical trial is to learn if a ketone drink can improve signs and symptoms of patients with a schizophrenia-spectrum disorder (SSD), or a bipolar-spectrum disorder (BD). The main questions it aims to answer are: Does a ketone drink improve information processing in patients with SSD/BD? Other …

18 years of age All Phase N/A
E Emma Visser, MSc

BioClock: Bright Light Therapy for Depressive Disorders

Bright Light Therapy (BLT) is a proven treatment for depression in seasonal and non-seasonal depressive disorders, as well as bipolar disorder. To make BLT more effective and practical in clinical settings and tailor it to individual needs, it is necessary to optimize the treatment approach, understand how the treatment works, …

18 - 65 years of age All Phase N/A
M Mari Husa, MD

Honest Open Proud for Psychotic and Bipolar Disorder in Norway

The purpose of this pilot study is to evaluate the feasibility, acceptability and efficacy of a Norwegian adaptation of the group-based intervention 'Honest Open Proud' among adults with psychotic and bipolar disorders in an outpatient setting.

18 - 65 years of age All Phase N/A

Non-invasive BCI and Application Verification for Depressed People

Major Depressive Disorder (MDD) is a serious mental illness and public health problem that poses threat to both physical and mental health. According to statistics from WHO, it is estimated that more than 350 million people worldwide suffer from depression, with a prevalence rate of 2.1% in China, which is …

12 years of age All Phase 4
M Megan C Ichinose, PhD

Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents

The present study is an open trial of ketogenic diets for adolescents and young adults (ages 12-21 yrs) in the depressive or mixed phases of bipolar disorder (BD). The investigators aim to determine whether combining standard of care pharmacological treatment for bipolar spectrum disorders with a 16-week ketogenic diet is …

12 - 21 years of age All Phase N/A
D Daniela Giansante, MSc

Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder

People with bipolar disorder (BD) are at high risk of relapse following hospital discharge, partly due to a lack of BD-specific expertise and resources within community services required for comprehensive treatment. Although clinical guidelines recommend combining medication and psychosocial support, and research shows that early intervention is associated with improved …

18 - 35 years of age All Phase N/A
J Joanne L Davis, PhD

Brief Treatment for Trauma Nightmares in Trauma-exposed Adults With Bipolar Disorder

Exposure, relaxation, and rescripting therapy (ERRT) is a promising psychological intervention developed to target trauma-related nightmares and sleep disturbances. Though further evidence is needed, ERRT has shown strong support in reducing the number and intensity of nightmares, as well as improving overall sleep quality in both civilian and veteran samples. …

18 years of age All Phase N/A
R Research Coordinator

Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study

Alcohol use disorders (AUDs) affect up to 60% of individuals with bipolar disorder during their lifetime and is associated with worse illness outcomes, yet few studies have been performed to clarify the causes of this comorbidity. Understanding biological risk factors that associate with and predict the development of AUDs in …

21 - 26 years of age All Phase N/A
K Kyle Cuklanz, B.S.

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

This is a randomized, double-blind, placebo-controlled proof-of-concept clinical trial to assess the efficacy and safety of Magnesium-vitamin B6in combination with treatment as usual for treating symptoms of depression, stress, and anxiety in patients with first episode bipolar I disorder.

18 - 50 years of age All Phase 2

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