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cancer-pain Clinical Trials

A listing of cancer-pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 123 clinical trials
J Joseph Arthur, MD

Effect of Olanzapine on Opioid Craving and Misuse Among Patients Receiving Opioids for Cancer-related Pain: A Pilot Double-Blind, Randomized Control Trial

To learn about the effectiveness of taking the antipsychotic medication olanzapine to help lower opioid craving.

18 - 100 years of age Both Phase 3
J Joseph G Winger, PhD

Meaning-Centered Pain Coping Skills Training for Cancer Pain

This study is a randomized controlled trial of a psychosocial pain management intervention called, Meaning-Centered Pain Coping Skills Training (MCPC). Patients with advanced solid tumor cancer and pain interference (N=210) will be randomized to MCPC or a standard care control condition. Patient-reported outcomes will be assessed at baseline and 8- …

18 - 100 years of age Both Phase N/A
S Silva Darrouj, HBSc

Chronic Cancer Pain Management Program

The goal of this research study is to evaluate an online inter-professional pain management program for survivors of breast cancer. The main questions it aims to answer: whether this treatment will help address the pain management concerns of patients, whether it is feasible to offer this treatment in the future …

18 - 100 years of age Both Phase N/A
A Agathi Karakosta

Opioid-free Anaesthesia in Breast Cancer Surgery

Background Various analgesic modalities are adopted for perioperative analgesia in breast cancer surgeries. Opioid-free and opioid-sparing techniques are gaining popularity due to the lack of opioid-dependent undesirable effects, including respiratory depression, urinary retention, nausea and vomiting, constipation, itching, opioid-induced hyperalgesia, tolerance, addiction, and immune system disorders. The goal of this …

18 - 99 years of age Female Phase N/A
K Kara Winchell

Pain Management for Head and Neck Cancer Survivors

This clinical trial improves an existing pain management program and tests its effect on head and neck cancer survivors. This trial aims to find a better program to improve pain-related physical functioning, mood, and quality of life in a sample of individuals who have undergone treatment for head and neck …

18 - 100 years of age Both Phase N/A
S Sung Gwe Ahn, MD, PhD

A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia

In 230 patients undergoing mastectomy, the investigators will compare opioid-free anesthesia (OFA) versus conventional opioid-based anesthesia in terms of chronic pain. The enrolled patients will be randomly assigned into two groups with 1:1 ratio. Chronic pain will be evaluated at 1 year after mastectomy based on the Breast Cancer Pain …

19 - 80 years of age Female Phase 3
C Caron Strahlendorf, MD

The Pain Squad+ Smartphone App To Support Real-Time Pain Management for Adolescents With Cancer

Pain negatively affects the quality of life of adolescents with cancer (AWC). It can also represent a high cost to the healthcare system and families. In response, our team has built a smartphone-based app, called Pain Squad+, which can give AWC real-time advice to manage their pain. The app uses …

12 - 18 years of age Both Phase N/A
M Matthew Patterson

Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain

This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer

18 - 75 years of age Both Phase N/A
C Carolina Fernández Lao, PhD

Pain Treatment in a Breast Cancer Population. PaiNEd Study.

The objectives of this study are: 1) To design and implement the PaiNEd system for the evaluation and treatment based on Pain Neuroscience Education (PNE) in cancer survivors with sequelae derived from medical treatments; 2) Study the effectiveness of the PaiNEd system integrated in a multimodal physical recovery program compared …

18 - 75 years of age Both Phase N/A

Prevention of Chest Pain in Chemo-treated Cancer Patients

This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment prior to the 5-FU treatment. The investigators hypothesize that aggressive management of ischemic risk factors in asymptomatic patients will …

18 - 100 years of age Both Phase N/A

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