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Liver Cancer Clinical Trials

A listing of Liver Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 207 clinical trials
D Danielle J. Vos, MD

Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM

The primary objectives of this phase I/II, prospective clinical trial, are to assess the optimal dose, efficacy, safety and immunological effect of ablation and intra-tumoral injection of a novel immuno-adjuvant (IP-001) for colorectal liver metastases (CRLM). The study consists of three parts, devided into two phases. Phase 1 is a …

18 years of age All Phase 1/2
C Crystal Engelage, PhD

Preoperative Ketogenic Diet for Reduction of Hepatic Steatosis

Non-alcoholic fatty liver disease is becoming increasingly common in Canada and throughout the world. Fatty liver can increase the risks of perioperative complications for those who need liver surgery. A ketogenic diet is low in carbohydrates and can be very effective in reducing liver fat content. The purpose of this …

18 years of age All Phase N/A
F Frida B Hansen

Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases

The SYLMET Trial is a randomized trial to compare simultaneous and two-staged resection of primary colorectal and synchronous liver metastases. This is an investigator-initiated, multicentre, randomized controlled trial to assess complications (primary endpoint), survival, cost-effectiveness, and quality of life (secondary endpoints).This trial will include patients with resectable primary tumour in …

18 - 80 years of age All Phase N/A
F Francesco Russano, MD

Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype

This is an monocenter, single arm, clinical investigation that evaluate the impact of the method on the objective response rate (ORR) of visceral lesions undergoing electrochemotherapy. Electrochemotherapy is a well-defined method for the treatment of cutaneous and subcutaneous metastases of different tumor histotypes. Although still limited, the various experiences in …

18 - 99 years of age All Phase N/A
F Francesco De Cobelli

Microwave Ablation for Treatment of Small Renal Tumors and Primary and Secondary Liver Neoplasms

The goal of this observational study is to collect data on efficacy and safety of microwave ablation (MWA) used to treat subjects with primary and secondary liver malignancies and renal malignancies. The main question it aims to evaluate the short, medium and long-term clinical course of patients treated with MWA. …

18 years of age All Phase N/A
K Karolina Grąt, PhD

TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery

Liver resection is the treatment of choice in patients with malignant liver lesions. Unfortunately, the surgery is not always an option, as in same patients the future remnant liver (FRL) is too small to supply all the functions. Therefore, some additional methods have been proposed to increase the size of …

18 - 80 years of age All Phase N/A
M M.R. Meijerink, MD, PhD

COLLISION RELAPSE Trial

The primary objective is to demonstrate superiority of neoadjuvant systemic therapy followed by repeat local treatment as compared to upfront repeat local treatment in patients with at least one locally treatable recurrent CRLM in the absence of extrahepatic disease.

18 years of age All Phase 3

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