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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 436 clinical trials
G George Kuchel, MD

The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults

The goal of this clinical trial is to test the effects of MitoQ supplementation in older adults and frail older adults with physical dysfunction and/or cognitive dysfunction. The main question[s] it aims to answer are: To compare vascular function, oxidative stress levels, and physical and cognitive function among older adults …

65 - 80 years of age All Phase 2
P Priska Birrer, Clinical Research Nurse

Evaluation of the Effect of Seasonality on Biological Age in Adults

This research aims to provide insights on how seasonal variations influence biological age and enhance the design and analysis of long-term lifestyle interventions targeting biological clocks. Aging is a gradual decline in cellular and organ functions, significantly increasing the risk of non-communicable and infectious diseases. Recent research has focused on …

40 years of age All Phase N/A
K Kathryn Wessell, MPH

Improving PCP Advance Care Planning for People With ADRD

This study will test the Dementia Advance Care Planning (AD ACP) Toolkit intervention to usual care in facilitating goals of care (GOC) discussions between People Living with Dementia (PLwD) and primary care team members over an 18-month period. The primary outcome is to assess the frequency and quality of GOC …

18 - 99 years of age All Phase N/A
H Helen SAVARIEAU, MSc

Evaluation of the Efficiency of the PRPP (Perceive, Recall, Plan and Perform) Task Analysis System on Support and Orientation Decisions for People With Aging Psychiatric Disorders (PATPV) Living in Independent Housing.

Over the past 30 years, mental health policy has been geared towards increasing the number of people receiving care in the community, with a reduction of over 50% in the number of general psychiatric beds. The WHO recommends the implementation of alternatives to hospitalization, through the development of outpatient and …

40 - 65 years of age All Phase N/A
S SU HSINFENG SU HSIN FENG

The Impact of Elderly Simulation Experience on Aging Knowledge, Attitudes, Empathy, Communication Skills and Learning Satisfaction for Facility Care- Workers in Long-term Care Institutions : An Action Research and Effectiveness Evaluation

This study aims to evaluate the effectiveness of an aging simulation experience course in enhancing the aging knowledge, care attitudes, empathy, communication skills, and learning satisfaction of care service personnel working in residential long-term care institutions.

20 - 70 years of age All Phase N/A

Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity

The prevalence of age-related chronic diseases (like obesity, type 2 diabetes and cardiovascular diseases) is mounting worldwide, reaching pandemic proportions. These age-related chronic diseases are associated with diminished skeletal muscle mitochondrial function in humans. Nicotinamide adenosine dinucleotide (NAD) is a coenzyme that regulates mitochondrial function, therefore, plays an important role …

60 - 80 years of age All Phase N/A
L Lindsay T Fourman, MD

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

People with HIV experience earlier impairments in physical function compared to people in the general population. They also exhibit an earlier presentation and more rapid development of frailty, a multisystemic syndrome of aging characterized by reduced activity, fatigue, slowness, weakness, and weight loss. While exercise can improve physical function in …

50 - 80 years of age All Phase 2
N Nancy Castellanos, BA

Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults

This is a randomized, double-blind, placebo-controlled, two-arm crossover clinical trial evaluating the effects of a patented age-reversal therapy, EGA®, compared to conventional nicotinamide mononucleotide (NMN) supplementation. The study will assess safety and efficacy in improving exercise tolerance and modulating biomarkers of aging in healthy older adults. The primary outcome is …

60 - 80 years of age All Phase N/A
S Stephanie G Iring-Sanchez, PhD

Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait

The goal of this intervention study is to determine if a new electronic stimulation device, similar to a TENS can improve balance and make walking easier in older individuals with reduced balance function. The main question aims to answer the following: Can using the device improve walking speed in older …

21 years of age All Phase N/A
C Chia-Hsun Hsieh, PhD

Can Exercise Ameliorate Immunosenescence and Thereby Reduce Relapse in Head and Neck Cancer Patients

Through the implementation of this three-year project, investigators expect to find a safe and effective exercise prescription for patients with oral cancer after surgery. The findings will encourage and promise and add further support to the concept that exercise prescription is worth implementation as part of care for the patients …

20 - 80 years of age All Phase N/A

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