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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 436 clinical trials
Z Zachary McKenna, PhD

Heat Waves and the Elderly - Cooling Modalities

The purpose of this study is to assess how well cooling modalities work in reducing cardiovascular stress of the elderly to heat wave conditions

65 years of age All Phase N/A
S Sylvie Nadeau, PhD

Development and Evaluation of TRIVEL Smart Bike Training Prescription Programs.

This pilot A-B study aims to develop and validate personalized training programs for older adults with decreased mobility on a Semi-Reclining Intelligent Stationary Bike prototype. The study also aims to assess the feasibility and acceptability of the training programs and to document their preliminary effects on physical health, perceived well-being, …

50 - 95 years of age All Phase N/A
P Pharmacology Translational Unit

The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population

The purpose of this study is to determine if the Fractionated Laser Resurfacing (FLR) procedure can protect one forearm/wrist from precancerous actinic keratosis (AKs) as well as prevent skin cancer in older subjects with active AKs. This study builds on a similar study ongoing at the Dayton Veterans Administration dermatology …

60 years of age All Phase N/A
M Marcus Ting, BSc (Hons) Science

Impact of Grape Powder Consumption on Eye Health and Glycemic Status in Singapore Older Adults

The purpose of this study is to understand the impacts of regular consumption of freeze-dried table grape powder on eye health and regulation of advanced glycation end products in Singapore older adults. The investigators hypothesize that regular consumption of freeze-dried table grape powder will promote improvements in eye health and …

60 - 85 years of age All Phase N/A

Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients

This study investigated the effect of Trendelenburg position on preventing post-induction hypotension in elderly patients undergoing abdominal surgery with general anesthesia. The patients will receive the 10° Trendelenburg position or supine position during anesthesia induction. The primary outcome is the area under a mean arterial pressure (MAP) below 65 mm …

65 - 90 years of age All Phase N/A
E Erol Ozmeral, Ph.D.

Understanding Aided Speech Perception in Noise

The overarching hypothesis to be evaluated using this protocol is that age-related hearing loss (ARHL) leads to shifts in the functional spatial boundaries between segregated and integrated auditory streams, and that hearing aid intervention that relies on directional processing schemes is most effective for those that have the poorest spatial …

18 - 80 years of age All Phase N/A
O Oscar Cumming, Dr.

A Study to Evaluate the Effects of the Combination of GI-102 With GIB-7 on Biomarkers of Aging in Healthy Adults and Cancer Survivors

This Phase 2a clinical study (GIANTS-1) aims to evaluate a novel dual-combination strategy using GI-102 and GIB-7 to address key pathological features of aging, including immunosenescence (the aging of the immune system), metabolic dysfunction, and gut-brain-muscle axis dysregulation.

18 - 80 years of age All Phase 2
J Jennifer Nguyen

Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals

The goal of this clinical trial is to see how small blood vessels respond to the stress of high intensity exercise, and if a safe and simple intervention called ischemic conditioning can protect blood vessels from the stress of exercise. Participants will come in for 3 study visits and get …

65 - 85 years of age All Phase 2
K Kerrie L Moreau, PhD

Cardiometabolic Consequences of the Loss of Ovarian Function

The menopause transition is associated with a decrease in artery health and an increased risk for weight gain in storing fat in the stomach area which may increase the risk for heart disease. The purpose of this research is to study how the decrease in estrogen at menopause changes artery …

20 - 45 years of age Female Phase 4

Pilot Intervention With Near Infrared Stimulation

The current study will test whether age-related cognitive and mood changes in older adults and those with Parkinson disease will be affected by near infrared (NIR) stimulation. The overall hypothesis, drawn from previous literature, is that exposure to NIR stimulation will have positive effects on brain health and will result …

65 - 89 years of age All Phase N/A

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