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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 436 clinical trials
C Caroline Li-Maloney, MSc

Enhancing Heat Resiliency in Older Adults During Indoor Overheating Via Heat Acclimation by Warm Water Immersion

As overheating in buildings is expected to increase as global warming continues, proactive measures to increase heat resiliency in heat-vulnerable older people are needed, especially for those without access to home cooling or reliable sources of electricity. While short-term heat acclimation through exercise in the heat has been shown to …

65 - 85 years of age Female Phase N/A
J John R Speakman, PhD

The Association Between Core Temperature and Health

The goal of this clinical trial is to learn if cold water drinking could promote body composition and further extend healthy lifespan in Chinese older adults. The main questions it aims to answer are: Does cold water drinking lower the body fat percentage? Will cold water drinking positively extend lifespan …

50 - 65 years of age All Phase N/A
J Jean-Marc Aimonetti, PhD

Studies Into Touch in Healthy Humans to Provide Sensory Feedback in Prostheses

Our sense of touch is essential to explore our environment and experience life and is based on signals from receptors in the body that are sensitive to different types of stimulation. The TACTHUM projects aims to investigate the fundamental firing of mechanoreceptors in the body to various external stimuli, with …

20 - 70 years of age All Phase N/A
C Caroline Moore

A Community-based Program That Supports Physical Activity, Healthy Eating, Social Participation and System Navigation in Older Adults

Physical mobility and social participation are needed to maintain independence and quality of life for adults over 55 years of age. Despite the known benefits of physical activity and dietary change programs for older adults, the best ways to deliver these interventions are not well understood. The goal of the …

55 years of age All Phase N/A
L Lakshmi Kannan, MS

Reactive Balance Training for Fall Prevention

The objective of this pilot study is to evaluate and compare the effect of three different perturbation based training devices on the reactive balance control among healthy young adults, healthy older adults, and neurologically impaired stroke individuals. Furthermore, the project aims to determine the feasibility and tolerability of 30-minutes of …

18 - 90 years of age All Phase N/A
R Robert Slevc, PhD

Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of life. By seeking to better understand post-stroke aphasia, this project lays the groundwork for development of …

18 years of age All Phase N/A
L Louis Bherer, PhD

A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors.

The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.

60 years of age All Phase N/A
J Jill Herch, BS

Acetate and Age-associated Arterial Dysfunction

Cardiovascular diseases are the leading cause of morbidity and mortality and contribute most to healthcare costs in the U.S. Age is the strongest cardiovascular disease risk factor, with >90% of all deaths from cardiovascular disease occurring in adults >50 years old. The age-associated increased risk of cardiovascular disease is due, …

50 years of age All Phase 2
D Dong-Xin Wang, MD, PHD

Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality

Sleep disturbances are prevalent in older patients with osteoarthrosis or fracture who are scheduled for knee or hip replacement surgery. The occurrence of sleep disturbances is associated with worse outcomes including increased risk of delirium and cardiac events, and worsened functional recovery. Dexmedetomidine is a highly selective α2-adrenergic agonist with …

65 - 90 years of age All Phase 4
T Tae-Ho Lee, PhD

The Role of the Locus Coeruleus in Age-related Distractibility

A growing body of research has highlighted the importance of frontal regions, at both the functional and structural levels, in age-related declines in attentional and cognitive processing. However, the underlying neurobiological pathophysiological changes in the brain that contribute to these declines are still largely unclear. The objective of this proposal …

18 - 75 years of age All Phase N/A

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