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lung-disease Clinical Trials

A listing of lung-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,215 clinical trials
P Ping Jiang

Multi-omics Study of Early-stage Lung Cancer with Distinct Phenotypes

The goal of this observational study is to investigate the multi-omics characterization early-stage lung cancer exhibiting distinct phenotypes including lung cancer associated with cystic airspaces, multiple primary lung cancers, and so on. The main questions it aims to answer are: What are the differences in pathogenesis of non-small cell lung …

18 years of age All Phase N/A
M Min Yan

The Effect of Perioperative Factors on Postoperative Outcomes After Lung Transplantation

Evaluate the influence of perioperative factors on postoperative outcomes in patients undergoing lung transplantation patients. To evaluate the feasibility of using pulmonary ultrasound to identify lung complications such as atelectasis and pulmonary edema after lung transplantation Observe the changes of perioperative inflammation and immune indexes after lung transplantation

18 years of age All Phase N/A
S Shiyue Li

Diagnostic Value of Confocal Laser Endomicroscopy (CelTouch) for Peripheral Lung Lesions

This study uses CelTouch to explore patients with lung lesions scheduled for lung biopsy. By comparing with preclinical CLE images and pathological images, CLE diagnostic criteria for benign and malignant lung lesions under the microscope will be established; the performance of CLE in diagnosing peripheral lung lesions will be validated …

18 - 80 years of age All Phase N/A
C Chris Roberts

A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae

The purpose of this study is to understand why some people experience long term effects, such as shortness of breath and fatigue, after a severe COVID-19 infection

18 years of age All Phase N/A
L Linda Karnay

Using ctDNA to Detect Minimal Residual Disease After Lung Cancer Resection

ctDNALung-Detect is an investigator-initiated single arm, multi-institution study designed to assess the ctDNA detection rate and its association with Relapse Free Survival (RFS) in operable stage T1-T4 (T3,T4 multifocal) N0M0 non-small cell lung cancer (NSCLC) patients.

18 years of age All Phase N/A
L Linfu Zhou, Doctor

DNA Methylation Combined With Artificial Intelligence Imaging to Identify Lung Nodules

Lung cancer is the leading cause of cancer deaths,and the key to reducing mortality in lung cancer patients is early diagnosis and treatment.Currently,peripheral blood DNA methylation is a novel in vitro molecular marker for tumors.Meanwhile artificial intelligence diagnostic system can further improve the diagnostic ability.The purpose of this study is …

20 - 80 years of age All Phase N/A

Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients

The goal of this observational and prospective study is to investigate changes in physical performance, lung function, and respiratory and peripheral muscle strength in patients during the postoperative period following coronary artery bypass grafting (CABG) and valve replacement surgery..

18 years of age All Phase N/A
J Jenna Wong, MSc

Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant

This study is designed to characterize the changes in diaphragm structure, function and biology during bridging to lung transplant by mechanical ventilation or extracorporeal life support.

18 years of age All Phase N/A
E Emilio Bria, Professor

Panomic Approach to Immune-Connected Assays in Small Cell Lung Cancer

The scope of the PICASSO project is to apply an innovative patient-based pan-omic approach to immune-assays, that will include multi-omics tumour characterization (genome, proteome, transcriptome), blood immune-cells and cytokine profiling, serological screening for paraneoplastic autoantibodies, clinical and metabolic measurements. The PICASSO project is aimed to validate in real world population …

18 years of age All Phase N/A

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

The goal of this observational prospective study is to determine the health impact of parenthood on United States (US) people with CF in the era of CF transmembrane regulator protein (CFTR) modulators. The investigators will collect physical and mental health data to comprehensively evaluate the impact of parenthood in CF …

18 years of age All Phase N/A

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