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lung-disease Clinical Trials

A listing of lung-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,186 clinical trials
E ESRA PEHLİVAN

Mechanical Properties of Peripheral and Accessory Respiratory Muscles in Chronic Obstructive Pulmonary Disease Patients

The biomechanical properties of accessory respiratory muscles and peripheral muscles of COPD and healthy subjects will be measured and compared with the MyotonPro device.

18 - 75 years of age All Phase N/A
B Bryan A Ross, MD, FRCPC, MSc (Epi, Physiol)

Predicting Acute Exacerbations of COPD Using Wearable Devices and Remote Monitoring Technology With AI/ML Models

This study is aimed to collect real-time physiological data using two wearable devices (a biometric ring and a biometric wristband), daily lung mechanical measurements by a handheld oscillometer, and participant-reported symptoms in patients with COPD remotely from their home environment. The data will be used to train and validate artificial …

40 years of age All Phase N/A
T Tristan Bonnevie

Predictive Properties of the 6-Minute Stepper Test for Mortality in COPD

Retrospective study aimed to answer the following research questions : What are the predictive properties of the 6-minute stepper in COPD for 2-year mortality in individuals with COPD ? What are the predictive properties of the 6-minute stepper in COPD for 5-year mortality in invididuals with COPD ?

18 years of age All Phase N/A
F Francesco Spannella

NT-proBNP Levels During Triple Therapy With Formoterol/Glycopyrrolate/Budesonide in Patients With COPD.

Observational prospective study to evaluate serum NT-proBNP levels in a population of COPD patients three months after the iniation of triple inhaled formoterol/glycopyrrolate/budesonide therapy.

50 years of age All Phase N/A
M Michael Dreher, Professor

Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease

The project will be pursued in our respiratory, autonomic nervous system physiology laboratory (Respiratory, autonomic nervous system physiology laboratory, Department of Pneumology and Intensive Care Medicine, RWTH Aachen University Hospital; Head of Department: Professor Michael Dreher). Overactivity of the sympathetic nerve activity (SNA) axis with "centrally" increased heart rate and …

18 years of age All Phase N/A
R Rimantas Benetis, PhD, Prof.

Respiratory and Cardiovascular Alterations in Patients With Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a major cause of disability and death worldwide. People with COPD often have cardiovascular diseases (CVDs) that are associated with increased risk for hospitalization and prolonged stay as well as all-cause and CVD-related mortality. Nevertheless, CVDs in patients with COPD are tend to be …

40 years of age All Phase N/A
S Sami Simons, MD PhD

Exploring Novel Biomarkers for Emphysema Detection

The goal of this clinical trial is to evaluate whether voice or capnometry, alone or in combination with other (non invasive) biomarkers can be used to detect emphysema on chest CT-scan in people with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is: • Can a …

18 years of age All Phase N/A
J Juan P de Torres, MD

Kingston Chronic Obstructive Pulmonary Disease (COPD) Multidimensional Long Term Follow up Cohort

Background: Chronic Obstructive Pulmonary (COPD) patients are the paradigm of the chronic complex patient. Their follow up can sometimes be difficult and challenging (1). There are patients with recurrent exacerbations that put an enormous burden on health care resources (2). They also have multiple comorbidities (3) that can sometimes make …

40 - 85 years of age All Phase N/A
T Takashi Niwa, MD

Zephyr Valve Japan Post-Marketing Surveillance

This is a multicenter, prospective, observational surveillance enrolling 140 consecutive patients with severe emphysema who are candidates for bronchoscopic lung volume reduction using Zephyr Endobronchial Valve at up to 20 centers across Japan and followed for 12 months.

18 years of age All Phase N/A
M Marc Beaumont, PhD

Validation of the French Version of the QASCI in Caregivers of Patients With COPD

This study aims to validate the French version of the QASCI questionnaire, initially written and validated in Portuguese language by Hipolito et al., to assess caregiving burden in chronic obstructive pulmonary disease (COPD). The realization of this validation is significant on several levels. First, since COPD is a systemic condition, …

18 years of age All Phase N/A

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