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lung-disease Clinical Trials

A listing of lung-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,186 clinical trials
S Sahar A Saddoughi, MD PhD

10°C vs 4°C Lung Preservation RCT

Despite lung transplantation (LTx) being the most effective treatment for end-stage lung disease, its success rate is lower than that of other solid organ transplantations. Primary graft dysfunction (PGD) is the most common post-operative complication and a major factor in early mortality and morbidity, affecting ~25% of lung transplant patients. …

18 - 80 years of age All Phase N/A
Y Yongchang Zhang, MD

Anlotinib Plus Immune Checkpoint Inhibitors for Lung Cancer

This study aims to explore the efficacy of Anlotinib with or without Immune Checkpoint Inhibitor in Standard Chemo-immunotherapy Failed Advanced NSCLC.

18 years of age All Phase 2/3
O Ole Hilberg

Navigate - Improving Survival in Vulnerable Lung Cancer Patients

Half of patients with lung cancer face a limited life span of one-year survival, which is characterized by severe physical and psychological symptoms. Differences in stage, comorbidity but also treatment may explain a large proportion of the social inequality in lung cancer survival. Some vulnerable patients may not receive first …

18 years of age All Phase N/A
C Chi-Fu J Yang, M.D.

Lung Cancer Screening in High-risk Black Women

The goal of this research study is to study U.S. Black women with a history of smoking to examine the feasibility, acceptability, and performance of low-dose computed tomography (LDCT) screening among this population. The name of the intervention used in this research study is: Low-dose computed tomography (radiologic scan) chest …

18 years of age Female Phase N/A
P Pieter Roel Tuinman, MD, PhD

Lung Ultrasound-Guided Fluid Deresuscitation in ICU Patients

Timely recognition and treatment of fluid overload can expedite liberation from invasive mechanical ventilation in intensive care unit (ICU) patients. Lung ultrasound (LUS) is an easy to learn, safe, cheap and noninvasive bedside imaging tool with high accuracy for pulmonary edema and pleural effusions in ICU patients. The aim of …

18 years of age All Phase N/A
M Moon Chen, M.P.H, Ph.D

Enhancing Lung Cancer Screening Through Human-Centered Intervention

The purpose of this study is to further understand the factors involved in increasing lung cancer screening.

50 - 80 years of age All Phase N/A
K Karen Mulholland Angelus

Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions. Clinically observed initial findings and an extensive body of research indicate regenerative treatments are both safe and effective for the treatment of multiple conditions.

18 years of age All Phase 1/2

Educating Smokers About Lung Cancer Screening Using Tobacco Quitlines

This implementation study will examine the best ways to refer heavy smokers to information about lung cancer screening.

18 years of age All Phase N/A
F François Labaste, MD, PhD

Advanced Goal-Directed Impedancemetry Strategy for Lung Resection Surgery

High-risk patients scheduled for lung resection surgery are increasing and theoretically eligible to perioperative individualized goal-directed fluid therapy (GDFT). However, thoracic surgery is challenging for intraoperative stroke volume (SV) and/or cardiac output monitoring because it requires lateral positioning, one-lung ventilation, and open-chest condition. Pulse contour analysis and esophageal Doppler have …

18 - 80 years of age All Phase N/A
E Endeavor Clinical Trials

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

The goal of this clinical trial is to evaluate the impact that ENV-101 has on lung function and key measures of fibrosis in adult patients with idiopathic pulmonary fibrosis (IPF). Another goal of this study is to better understand the safety and tolerability of ENV-101 in this patient population.

40 years of age All Phase 2

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