Advanced Filters
noise

heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 844 clinical trials
A Ana Lopes, McS

Cardiac Remodelling Following Endovascular Repair of the Aorta

To assess the effects of endovascular aortic repair on cardiac morphology and function

18 years of age All Phase N/A
M Matthias Heringlake, Prof. Dr. Med.

Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.

All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both …

18 years of age All Phase N/A
H Helena Dominguez, MD, PhD

The Cardio-share Telemedicine Cross-sector Collaboration Model for Managing Vulnerable Patients With Heart Failure

The goal of this observational study is to explore the potential of implementing a telemedicine-based cross-sector collaboration model to manage patients with frequent admissions with decompensated heart failure. The main question(s) it aims to answer are: Characterization of conditions that make these patients vulnerable Description of key-elements that makes possible …

years of age All Phase N/A

Baduanjin-eight-silken-movement With Self-efficacy Building for Patients With Chronic Heart Failure (BESMILE-HF Study)

Chronic heart failure (CHF) is a major and growing public health problem and poses economic burden on the society. There is a need for a safe, equipment-free, low-cost, and easily implemented exercise-based cardiac rehabilitation program for CHF patients in China. Baduanjin exercise, translated as 'eight silken movements', is one of …

18 years of age All Phase N/A
G Giosafat Spitaleri, M.D.

Evaluating Residual Congestion at Discharge in Acute Heart Failure Patients

Treatment of congestion is one of the main goals in patients hospitalized for acute heart failure. Nevertheless, current evidence shows that decongestion is often not achieved and that residual congestion at discharge is strongly associated with poor outcomes. While this association has been demonstrated, previous studies have primarily focused on …

18 years of age All Phase N/A
D Department

ChAracterization of Patients and Treatment OUtcomes in Severe Tricuspid Regurgitation

The goal of this observational study is to characterize the population of patients qualified for transcatheter tricuspid valve interventions (TTVI). It is expected to: Describe the profile of patients qualified for TTVI Establish the most common causes for disqualification from TTVI Evaluate the immediate and long-term efficacy of TTVI Evaluate …

18 years of age All Phase N/A
O Olivia Lovegreen

A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

Severe skeletal wasting and catabolic weight loss are highly common among patients with heart failure with reduced ejection fraction (HFrEF). This prospective randomized controlled trial will compare changes in the muscle mass in the arms and the legs (appendicular lean mass) in patients with HFrEF randomized between 3 groups of …

18 - 100 years of age All Phase N/A
R Ryan Li, MASc

Ted Rogers Understanding of Exacerbations in Heart Failure 2: Monitor

Heart Failure (HF) is a complex disease associated with the highest burden of cost to the healthcare system. The cardiopulmonary exercise test (CPET) is instrumental in determining the prognosis of patients with HF. This multicentre study will validate whether aggregate biometric data from the Apple Watch combined with demographic, cardiac, …

18 years of age All Phase N/A
O Oliver Rider

The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction.

This study looks at the effects of weight loss in people who have heart failure with reduced ejection fraction (HFpEF) and are overweight or obese. The main questions it aims to answer are whether weight loss in this group of people improves: The heart's shape and how well it pumps …

18 - 85 years of age All Phase N/A
M Marek Sramko, MD, PhD

Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure

This study will evaluate the feasibility and safety of achieving therapeutic concentrations of beta-hydroxybutyrate using continuous infusion of D-beta-hydroxybutyrate monoester administered via a nasogastric tube in patients with acutely decompensated heart failure with reduced left ventricular ejection fraction.

18 years of age All Phase 4

Simplify language using AI