Advanced Filters
noise

Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,234 clinical trials
T Trine T.H. Sainte-Marie, Masters

PERSONAE - a Personalized Online Treatment of Depression

The goal of this clinical trial is to determine whether a personalized online treatment for depression, delivered via an app (PERSONAE), is effective in treating mild to moderate depression in adults. The study will also assess the safety of the Monsenso app. The main questions it aims to answer are: …

18 years of age All Phase N/A
M Mengyao Li, Mphil

EMA and mHealth in Preventing Postpartum Depression

This proposed study aims to develop and examine the feasibility, acceptability, and preliminary effectiveness of a proactive intervention model that combines brief psychological counselling, Ecological Momentary Assessment (EMA), mHealth-based psychological support, and CBT-guided telephone counselling to prevent postpartum depression (PPD).

18 years of age Female Phase N/A
H Hsiang-Yuan Lin, MD

Psilocybin for Treatment-Resistant Depression in Autism

We propose a first-of-its-kind open-label clinical trial to investigate the feasibility, tolerability, and safety of administering psilocybin in autistic adults with treatment-resistant depression (TRD). In this study, 20 participants (intellectually able and fluent-speech adults) with autism and co-occurring TRD will receive around 20 hours of manualized psychotherapy that has previously …

18 - 65 years of age All Phase 1
S Sudha Prathikanti, MD

Treating Major Depression With Yoga Mono-therapy

The goal of this single-center, single-blind, randomized, controlled, parallel group, interventional trial is to evaluate antidepressant efficacy of yoga monotherapy of 12-weeks duration in 180 adults meeting diagnostic criteria for mild-to-moderate major depression at the Zuckerberg San Francisco General Hospital. Researchers will compare the yoga interventions to an education control …

18 years of age All Phase N/A
A Antoine Yrondi

Treatment Resistant Depression and Vagus Nerve Stimulation

Depression is a common illness, affecting 17% of the population over the course of a lifetime. A third of depressions relapses and progresses to recurrence and resistance to treatments. Despite the optimization of antidepressant medical strategies, 20 to 40% of depressions do not respond to treatment. This is particularly worrying …

18 years of age All Phase N/A

Stories That Empower Mothers and Postpartum Depression

Postpartum depression is a condition that occurs after birth and is difficult for mothers. Research shows that experiencing postpartum depression once increases the risk of experiencing it in subsequent pregnancies. At the same time, there are findings in the literature that pregnant women with postpartum depression experience mental difficulties, anxiety …

18 years of age Female Phase N/A

TACS on High-inflammatory and Refractory Depression

This study is a randomized controlled trial with a duration of 12 weeks (4 weeks of intervention + 8 weeks of follow-up). The participants are patients with treatment-resistant depression (TRD) and high inflammatory activity (n=52). The study aims to clarify the effectiveness of 15mA, 77.5Hz transcranial alternating current stimulation (tACS) …

18 - 55 years of age All Phase N/A
B Brijesh Patel, DO

AI Platform for Fatigue and Depression Detection

This observational study evaluates the accuracy of the Okaya AI platform in detecting fatigue and depression in cardiology patients, comparing its assessments to PHQ-9 and Fatigue Assessment Scale scores.

18 - 99 years of age All Phase N/A
M Michael J McCarthy

Nutritional Intervention for College Students With Depression

The goal of this clinical trial is to assess the feasibility of nutritional interventions in college students with depression. The main outcomes it aims to measure are: Nutritional content, meal timing, and sleep patterns in college students with depression Feasibility of nutritional interventions (Mediterranean Diet and Time-Restricted Eating + Mediterranean …

18 years of age All Phase N/A
H Hongxing Wang, MD & PhD

Effect of WBT for CI With Depression

This randomized controlled trial aims to explore the therapeutic effects of Well-Being Therapy (WBT) on patients with Chronic Insomnia accompanied by depressive symptoms.

8 years of age All Phase N/A

Simplify language using AI