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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,234 clinical trials
Y Yuan Cao

Music Program for Hong Kong Adolescents: Improving Emotion Regulation and Reducing Depression, Anxiety, and Loneliness

This study is a clinical trial that aims to test and validate a music-based program called "Tuned In" in helping adolescents in Hong Kong improve their mental well-being. The researchers want to find out if the program can help participants enhance their ability to regulate their emotions, reduce mood symptoms …

16 - 19 years of age All Phase N/A
T Theodora Anastasiou, PhD Candidate

Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT

This single-blinded, multicentered, randomized controlled trial aims to evaluate the effectiveness of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) compared to Treatment-as-Usual (TAU) in reducing post-traumatic stress symptoms among unaccompanied refugee minors (UAMs) residing in accommodation centers and Supported Independent Living (SIL) programs in Greece. Participants aged 15-18 will be randomly assigned …

15 - 18 years of age All Phase N/A
L Laura Klinger, PhD

Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

Autistic adults are at a greater risk for mental health problems compared to the general population, with 50% meeting criteria for a co-occurring psychiatric condition. Depression and anxiety are the most common of these conditions among autistic adults, contributing to long-term detrimental effects on health, day-to-day functioning, and quality of …

18 years of age All Phase N/A

Distribution of Mood and Personality Characteristics and Their Influence on Treatment Compliance

This study intends to investigate the personality and psychological characteristics of OSA patients using classical standard scales and obtain treatment information and adherence data through prospective follow-up to summarize the distribution characteristics of mood and personality characteristics of OSA patients and their influence on treatment adherence. A thorough understanding of …

18 - 70 years of age All Phase N/A
S Sabrina Sanchez, MD

Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

Animal assisted therapy (AAT) with dogs has been shown to be beneficial for a wide range of patients with both acute and chronic illnesses, including spinal cord injuries, heart failure, myocardial infarctions, strokes, cancer, post-traumatic stress disorder, and depression. Studies have also demonstrated that even in healthy adults, the presence …

18 years of age All Phase N/A
E Eva Velthorst, PhD

Online Therapy Youth, Equivalent to Treatment As Usual?

With growing waiting lists in specialized youth mental health care (sGGZ) and shortages of care staff, finding creative solutions to respond to this scarcity issue is important. Online treatment is an example of this, which, especially for young people growing up in a digital age, can be an appropriate and …

12 - 18 years of age All Phase N/A

RCT: the Effectiveness of LifeHack in Improving Mental Wellbeing in University Students.

Psychological issues are common among university students and affect mental wellbeing. The Caring Universities (CU) project, involving nine Dutch universities, aims to enhance students' mental health through an annual online questionnaire and a platform offering guided eHealth interventions. One intervention, LifeHack, utilizes cognitive behavioral therapy-based modules to improve mental wellbeing …

16 - 99 years of age All Phase N/A
D David Crowley

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation

The study will investigate whether a nociceptin receptor antagonist will normalize neural and behavioral processes of approach/avoidance decision-making in unmedicated individuals with major depressive disorder (MDD) and anxiety disorders. More specifically, the study aims to investigate dysregulation within (1) corticostriatal-midbrain circuitry and (2) nociceptin/orphanin FQ peptide and the nociceptin receptor …

18 - 45 years of age All Phase 2
J Jyoti Mishra, PhD

Meditative Neurofeedback for Depression

The goal of this open-label single-arm study is to test a meditative neurofeedback intervention for depressed mood.

18 years of age All Phase N/A
A Adriana Carneiro AM Adriana Carneiro, DsC.

Psychoeducational Group for Depression

The study aims to investigate the efficacy of a psychoeducational program as an adjunctive treatment for depression. The study will involve 338 patients diagnosed with Major Depressive Disorder (MDD) of moderate severity. Participants will be randomly assigned to receive either Treatment as usual (TAU) alone or TAU plus the psychoeducational …

18 - 59 years of age All Phase N/A

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