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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,234 clinical trials
K Karly M Murphy, PhD

Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

Our team has developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression. This tool includes one psychoeducation component and four components that are based on evidence-based interventions for depression. The goal of this study is to test which component or …

15 - 39 years of age All Phase N/A

Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

The study will examine the role of digital wellness modules (brief mindfulness and light to moderate physical exercise) delivered through a smartphone wellness application and their short-term effects on health behavior motivation and change, and longer-term quality of life and non-pathological affective states.

18 - 65 years of age All Phase N/A

Auricular Acupuncture in Patients With Advanced Cancer: a Randomized Clinical Trial.

In the present study, the effect of ear acupressure treatment according to the NADA protocol on the quality of life of patients with advanced tumour diseases. (all stages) will be investigated. Furthermore, the effect of ear acupressure on anxiety and depression, pain, fatigue and sleep of the patients will be …

18 - 70 years of age All Phase N/A
A Amanda Summers, MA

Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST)

FOREST is a positive emotion skills program designed to target mental health and coping needs for frontline violence prevention workers at UCAN. Ten skills are taught over a period of nine months during existing meetings and wellness activities, as well as in online modules in UCAN's Learning Management System (LMS). …

18 years of age All Phase N/A
L Lucia Knight, PhD

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV. However, posttraumatic stress (associated with intimate partner violence and/or other traumas) and depression negatively impact PrEP adherence among women in SA. Addressing posttraumatic …

15 years of age Female Phase N/A
M Mandeep Singh, MBBS, FRCPC

Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Frontline Health Care Workers (The HCW-CBTi Study)

The COVID-19 pandemic has resulted in increased workload and concerns about personal and family safety for frontline healthcare workers (HCWs), which can lead to decreased well-being and worsening mental health. Sleep disruption is particularly prevalent among HCWs providing frontline COVID-19 care. It can have direct consequences on their cognitive and …

years of age All Phase N/A
S Smita N Deshpande, M.D.

Cognitive Enhancement in Unipolar Depression With Yoga

It is evident from recent studies that cognitive deficits persist even after remission of depressive episode. Hence, in this study, the investigators would like to see whether specific Yoga practice will help in enhancing cognitive abilities in this population.

18 - 60 years of age All Phase N/A
U Ulrich Schu, MD

Enoxolone in Major Depression - Biomarker-outcome Relationship

This study will test Flourish, a digital suicide prevention intervention for cyberbullied youth, within schools. Specifically, the study aims to: Examine if Flourish is effective and can be feasibly delivered within schools among middle and high school students who are experiencing cyberbullying and suicide risk factors. Feasibility will be evidenced …

18 years of age All Phase 1/2
P Paul Thomas

Transcranial Direct Current Stimulation for Depression

This study will test the efficacy of transcranial direct current stimulation (tDCS) combined with mindfulness, remotely-delivered using a telemedicine protocol in 25 adults with unipolar depression.

22 years of age All Phase N/A
A Anette Omuro

Effect of Tao Calligraphy Meditation and Energized Water on Depression

The goal of this controlled randomized clinical study is to learn if a Tao Calligraphy Mindfulness and Energized water Practice works to improve Unipolar Depression. The main questions it aims to answer are: Does Tao Calligraphy Mindfulness practice and drinking Energized water improve the subjective symptoms of Unipolar Depression in …

19 years of age All Phase N/A

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