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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,234 clinical trials
C Cadence F Bowden, MSW, MPH

Antidepressant Adherence for Depressed Adults in Primary Care

The goal of this study is to test ways to help people improve their health and manage their medication for depression. This study will measure both medication adherence and depression outcomes.

21 - 64 years of age All Phase N/A
N Nicholas Van Dam, PhD

Dose-Response Effects of Mindfulness Meditation

The goal of this randomized controlled trial is to test for evidence of dose-response effects in a sample of healthy adults with little to no prior experience with meditation. The main question it aims to answer is whether larger doses of mindfulness meditation yield greater positive changes in wellbeing than …

18 - 65 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Characterization and Treatment of Adolescent Depression

This research study seeks to find causes and treatments of depression in teenagers. The study goals are to increase our knowledge of treatments for depression and understand how the brain changes when teenagers have depression. The study will also compare teenagers with depression to those without mental health diagnoses. This …

11 - 25 years of age All Phase N/A
Z Zhou Xinyu, Doctor of Philosophy

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)

This project aims to investigate the effectiveness of existing common antidepressants and to provide new evidence for depressed children and adolescents who are not responding to their first treatment.

13 - 18 years of age All Phase 1/2
C Christopher G Beevers, PhD

Confirmatory Efficacy Trial of Attention Bias Modification for Depression

The goal of this clinical trial is to compare the efficacy of two related, but different ABM (Attention Biased Modification) treatments for depression in adults with elevated symptoms of depression. The main aims are: Aim 1:examine whether gamified ABM leads to greater change in the primary and secondary outcomes than …

18 - 70 years of age All Phase 0

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

Clinical Study on the efficacy and safety of HAIC(GEMOX)and Lenvatinib combined with Adebrelimab neoadjuvant therapy for resectable Intrahepatic Cholangiocarcinoma with high-risk recurrence factors.

18 - 75 years of age All Phase 3
M Mari Berglund

A Randomized Controlled Study of Digitalized Cognitive Behavioral Intervention for Antenatal Depression

The main objective of the current research project is to evaluate the effectiveness of the digitalized cognitive behavioral therapy program including telephone coaching for antenatal depressive symptoms. The participants are screened from the general population of pregnant women, as a part of the routine maternity health care check-ups. Mothers with …

18 - 55 years of age Female Phase N/A
L Liz Stevenson, JD

Reaching Out to Distressed Medical Residents, Fellows and Faculty

The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and suicidal thoughts. The screening and ability to interact online with a clinician anonymously are hypothesized to increase willingness …

18 years of age All Phase N/A

Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments

The study involves multiple retrospective analyses to understand the utilization of mental health treatments provided at Greenbrook and their effectiveness

5 - 100 years of age All Phase N/A
D Deepak Tugnawat

Improving Outcomes in Depression in Primary Care in a Low Resource Setting

The OptimizeD study aims to improve outcomes in depression in primary care in India. This study will randomize 1500 patients with moderate to severe depression to either psychotherapy based on behavioral activation called the Healthy Activity Program (HAP) or antidepressant medication (fluoxetine). The study has two primary objectives: Use patient …

18 years of age All Phase 3

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