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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,234 clinical trials
J Jonathan D Singer, PhD

Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD

This project aims to adapt, implement, and evaluate a Dialectical Behavior Therapy skills training group intervention for aging adult family caregivers of person with Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) to reduce suicidality. By adapting this modality, the investigators will provide a scalable intervention tailored for this high-risk …

50 - 120 years of age All Phase N/A
M Maria Traverso

Mentalizing and Epistemic Trust in Patients With Anxiety and Depression.

This randomized clinical trial aims to evaluate the effects of mentalization-based group psychotherapy in patients diagnosed with anxiety and/or depression disorders. In total 100 users of mental health communitary services will be recruited for this study. Participants will be randomized in two parallel groups: to receive usual acceptance and commitment …

18 years of age All Phase N/A
U Ulrich Stangier, Professor

Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression

The aim of this study is to test the relative efficacy of Process-based Therapy compared to traditional CBT delivered in routine practice (r-CBT) for difficult-to-treat anxiety disorders and depression.

18 - 65 years of age All Phase N/A
P Paula Carlson, BS

Effect of Vagal Nerve Stimulation on Gastric Motor Functions

The specific aim of this study is to compare simultaneous assessment of gastric emptying and gastric accommodation in response to a caloric meal In patients who have previously undergone activation of left cervical VNS for the treatment of medication-resistant depression. Our hypothesis is that cervical VNS increases gastric accommodation and …

18 years of age All Phase N/A
T Traci Thompson, MD

Cocooned Moms Study

The Cocooned Moms Study is a pre- and post-design study primarily aimed at reducing stress, depressive symptoms, and blood pressure among expectant Black women by providing them with free access to the InovCares mobile app. InovCares is a culturally-sensitive telehealth platform designed for community-based care coordination in maternal care. It …

18 years of age Female Phase N/A
K Kara Murias

Brain STimulation for ANxiety and Depression in Youth

In this open-label trial, the overall aim is to determine if TMS treatment can improve anxiety and depression in a broad group of children and youth referred by physicians.

6 - 18 years of age All Phase N/A
K Katherine E Burdick, PhD

Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II

This study is a clinical trial that evaluates what drives patient engagement and tests the impact of two strategies-automated motivational push messaging and coach support-to improve engagement with an evidence-based mobile app intervention for depression and/or anxiety.

18 - 75 years of age All Phase N/A
B BRISK Study Team

Behavioral Health Program for Short-Stay Nursing Facility Residents & Care Partners

The goal of this clinical trial is to test a behavioral health program (Interventions for Stressful Transitions in Later Life, InSTILL) for skilled nursing facility residents and their primary support person. The main questions it aims to answer is whether the program is program is feasible, satisfactory, and helpful. The …

18 years of age All Phase N/A
Y Yanghua Tian, PhD

Multimodal Clinical Study of Electroconvulsive Therapy and Magnetic Seizure Therapy

To compare the efficacy and tolerability of Electroconvulsive Therapy (ECT) and Magnetic Seizure Therapy (MST) in patients with major depressive disorder (MDD).

12 - 80 years of age All Phase N/A

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

The purpose of this study is to evaluate how well JNJ-89495120 works (anti-depressant effects) and how well it is tolerated as compared to placebo on reducing the symptoms of depression in participants with major depressive disorder (MDD).

18 - 64 years of age All Phase 2

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