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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,220 clinical trials
W Wendy WC Rongen, MSc

Depression and Suicide Prevention in Adolescents Attending Special Schools

Depression is a major public health concern. In Dutch adolescents, the prevalence of major depressive disorder is estimated at 3.8%, and one in five adolescents report depressive symptoms. Depression is a risk factor in adolescent suicide. School-based prevention programs, for example the STORM approach, are effective in decreasing depressive symptoms …

12 - 18 years of age All Phase N/A
J Judy R Wilson, Ph.D.

Effects of Exercise and Virtual Reality on Depression

This study is evaluating the effects of riding on a cycle ergometer while experiencing virtual reality to determine its effect on mood.

18 - 65 years of age All Phase N/A
G Gladys Ibanez

A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV

The goal of this randomized clinical trial is to learn if tai chi/qigong decreases depressive symptoms among older people living with HIV compared to a health education class. The main questions it aims to answer are: Does tai chi/qigong reduce depressive symptoms among older people living with HIV more than …

50 - 75 years of age All Phase N/A
G Gisela Jimenez-Colon, PhD

A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior

This study will test a model of providing treatment to Latinx/Hispanic youth, who experience suicidal thoughts and behavior, and their caregivers. An affirmative and culturally relevant treatment will be provided to all youth and half of the families will be assigned to the additional support of a community health worker …

12 - 18 years of age All Phase N/A
K Karin Hediger, Prof. Dr.

Dog Presence and Oxytocin on Trust Towards Therapists

Oxytocin has been proposed as a neuroendocrine mechanism that may mediate the relationship between dog ownership and positive health outcomes and be linked to human-dog interactions and is thought to be a mechanism of interspecies bonding. While the role of oxytocin in human bonding behaviours and social behaviour, in general, …

18 years of age All Phase 2/3
W Wing Sze Chow

Social Worker-led Mindfulness-based Intervention for Older People

Preliminary findings from a previous study conducted by the investigators suggest that a task-shared approach with modified mindfulness-based cognitive therapy (MBCT) supported by social workers is beneficial in managing depressive symptoms and improving mindful non-reactivity among older adults. However, the possibility for social workers to lead a mindfulness-based intervention (MBI) …

60 years of age All Phase N/A
J Jami Young, PhD

Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)

This pilot randomized controlled trial will examine the feasibility, acceptability and preliminary efficacy of an adolescent depression prevention program, Brief Interpersonal Psychotherapy-Adolescent Skills Training (B-IPT-AST), in primary care.

13 - 17 years of age All Phase N/A
M Marieke Wouters, PhD

Implementation of Bright Light Therapy ID

Many adults with intellectual disabilities (ID) have depressive symptoms, which negatively impact their quality of life. A lot of of the non-medicinal forms of treatment are not or hardly suitable for people with ID. Bright light therapy (BLT) seems to be a good option. Earlier research has shown that BLT …

18 years of age All Phase N/A
N Nathan

Feasibility and Effects of a Blended Baduanjin Exercise and Green Tea Consumption Program on Depressive Symptoms, Gut Microbiota and Quality of Life in Older Adults

Depression is a common mental health issue in older adults, often manifesting as insomnia, low mood, vague somatic complaints, cognitive decline, and recurrent thoughts of death or suicide. Even subthreshold depressive symptoms in late life significantly impair quality of life. In Hong Kong, recent data show high prevalence of depressive …

65 - 84 years of age All Phase N/A
R Roger McIntosh

Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)

The purpose of this randomized controlled trial is to understand how a cognitive-behavioral treatment (a form of psychological treatment) for depression changes the gut microbiome (micro-organisms that regulate the health of the gut), immune system, and the brain functioning in people living with HIV.

18 years of age All Phase N/A

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