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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,179 clinical trials
Z Zhou Xinyu, Doctor of Philosophy

Digital Cognitive Behavioral Therapy for Chinese Adolescents With Depressive Symptoms(CADS-D )

CADS-D aimes to evaluate the effectiveness and feasibility of a newly DCBT program for Chinese adolescents with depressive symptoms.

12 - 18 years of age All Phase N/A
A Anissa Megzari

Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

Up to 40% of individuals with alcohol use disorder (AUD) experience depression, which increases the risk of early relapse. Depression can cause relapse to occur 3 times faster in individuals with AUD who experience depressive symptoms at discharge. No treatments have been approved for individuals with both AUD and depression. …

18 years of age All Phase 3
N Nili Solomonov, PhD

Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality

The investigators hypothesized that during the 9-week course of Engage \& Connect treatment there will be an increase in brain functions of the Positive Valence System which in turn will lead to reduction in suicidality.

50 - 80 years of age All Phase N/A
L Laura M Vowels, PhD

Evaluating the Impact AI Avatar-led Mental Health Interventions for Keeping Employees in Work

This study will examine whether an artificial intelligence (AI) avatar-led mental health programme can help employees experiencing symptoms of depression. The programme delivers structured, self-guided psychological support over several short sessions that participants complete online over a period of several weeks. Approximately 50-80 adults will take part. Participants will be …

18 years of age All Phase N/A
J Juliana zambrano, MD, MPH

A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression

This is a pilot clinical trial to assess the feasibility, safety, and preliminary efficacy of ketamine-assisted group therapy for Spanish-speaking adults with depression

18 - 64 years of age All Phase 1/2
C Caitlin Holley, Ph.D.

Veteran's Perceptions of Ketamine-Assisted Psychotherapy for Depression and End-of-Life

The goal of this exploratory, mixed-method design study is to gather qualitative and quantitative data obtained through interviews and questionnaires with veterans who are currently enrolled at the VA for healthcare. The main question this study aims to answer is: How do veterans aged 65+ who are enrolled for care …

65 years of age All Phase N/A
W Walker SH Au

Evaluation Study of Medical-Social Collaboration Model for Middle-aged and Older Adults With Depressive Symptoms

The goal of this clinical trial is to learn if a medical-social collaboration model works to reduce depressive symptoms in middle-aged and older adults with subsyndromal depressive symptoms who are waiting for their first psychiatric appointment. Secondary outcomes of the study include reduced anxiety symptoms, reduced loneliness, reduced rumination, reduced …

45 years of age All Phase N/A
B Berthold Langguth

Intermittent Theta Burst Stimulation for Maintenance Therapy in Depression

This is a randomized, multi-center, open-label study in which patients with depression who responded to an open-label treatment with intermittent theta burst stimulation (iTBS) will receive this procedure as maintenance therapy. The patients will be randomized to two study arms. The arms differ in the frequency of stimulation (standard iTBS …

18 - 70 years of age All Phase N/A
M Mary Goldsworthy

Lay-Delivered Behavioral Activation in Senior Centers

In response to large numbers of senior center clients who suffer untreated depression and the dearth of geriatric mental health providers, the investigators have simplified Behavioral Activation to be delivered by lay volunteers ("Do More, Feel Better"; DMFB). The focus of Behavioral Activation is to guide clients to reengage in …

60 years of age All Phase N/A

Motivational Multicomponent Lifestyle Interventions as a Supportive Treatment for Depression in Primary Health Care

The investigators aim to examine whether a motivational multicomponent lifestyle intervention as a supportive treatment for depression has a beneficial effect on recovery from depression in a primary health care setting.

18 years of age All Phase N/A

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