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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,234 clinical trials
A Ana Tyrkala, PhD

Mental Health in Primary Care

The goal of this study is to evaluate in an effectiveness-implementation type I hybrid trial, an enhanced version of eHealth Familias Unidas for reducing depressive, anxious symptoms and suicide behavior in Hispanic youth. The study will use a randomized rollout design with 18 pediatric primary care clinics in the South …

12 - 16 years of age All Phase N/A
A Anthony Doufas, MD, PhD

The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

18 - 70 years of age All Phase N/A
A Alexander McGirr, MD PhD

iTBS+D-Cycloserine for Youth Suicide

Background and Rationale: Suicide is the second leading cause of death in Canadian Emerging Adults (EAs; 18-24yrs). Current treatments for suicidal thoughts and behaviors are limited and novel treatments are required to save lives. Transcranial Magnetic Stimulation (TMS) is a non-invasive neurostimulation treatment for major depressive disorder, a mental health …

18 - 24 years of age All Phase 2
L Leticia Hernandez Galan, PhD

Affect of Duavive on Mood & Anxiety Symptoms

This study evaluates the impact of conjugated estrogens/ bazedoxifene (CE/ BZA) on the mood (depression and anxiety) in peri- and early menopausal women.

45 - 60 years of age Female Phase 1
M Moran Amit, MD

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

To learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy on depression and/or anxiety in participants who are being treated for advanced cancer.

25 years of age All Phase 2
C Cindy McEvoy, MD, MCR

The Development of PATH, a Program to Support NICU Parent Mental Health Through the Transition From Hospital to Home

The objective of this study is to develop and pilot test a telehealth-based mental health screening and engagement program that supports parents as their infants transition home from the NICU. The program will use a stepped-care approach to screen parents for depression, anxiety, and PTSD; provide a brief behavioral intervention …

years of age All Phase N/A
W Winsome Lam, PhD

Acceptance and Commitment Therapy-based Intervention for Parents of a Child With Medical Complexity

A pilot randomized controlled trial of an Acceptance and Commitment Therapy-based intervention will be conducted to decrease psychological symptoms, while increase psychological flexibility for parents of a child with medical complexity during their difficulties.

18 years of age All Phase N/A

Maternal Well-being in the Perinatal Period

The goal of this observation study is to investigate the mental health status of women experiencing their first pregnancy, with particular attention to anxiety and depression symptoms, feelings of loneliness, and the quality of defense mechanisms employed.

years of age Female Phase N/A
M Marcello Cottini

Mouthpiece With Integrated Cheek Support vs. Manual Cheek Support During Respiratory Oscillometry

The study aims to evaluate the measurement accuracy of respiratory impedance during oscillometry (or Forced Oscillation Technique - FOT) under the following conditions: 1)The subject's cheeks are manually supported by an expert (Gold Standard method), 2) The subject's cheeks are supported by an integrated cheek support in the mouthpiece. It …

5 - 75 years of age All Phase N/A
N Niesha Darden

Postpartum Care in the NICU (PeliCaN) Transitions

This is a randomized controlled trial of a dyad-centered, doula support and healthcare coordination model of care in a large urban neonatal intensive care unit (NICU), which serves a high-risk, low-income, majority Black population. In addition to doula support and coordination of care in the NICU, there will be a …

16 years of age Female Phase N/A

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