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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,220 clinical trials
Y YI-CHIEH CHUNG, Registered Nurse

Psychological Well-Being, Depression, and Health-Related Quality of Life in Adults With Type 2 Diabetes: A Cross-Sectional Study

This prospective cross-sectional observational study aims to explore the relationships among psychological well-being, depression, and quality of life in patients with type 2 diabetes attending the outpatient metabolic clinic at National Taiwan University Hospital. The study will collect data using standardized instruments, including the EQ-5D Health-Related Quality of Life Questionnaire, …

18 years of age All Phase N/A
S Sanne V. Hovgesen, MD

Lithium Versus Cariprazine in the Acute Phase Treatment of Bipolar Depression (DUAG9)

The goal is to study the effect of lithium compared to cariprazine in patients with depression in a bipolar disease. The main question it aims to answer is: Difference in change between the two groups from baseline to after 8 weeks treatment on Hamilton Ratings Scale for Depression, 6-item version …

18 - 65 years of age All Phase 4
V Vanessa Evans

Light and Ion Maintenance In Treatment for Depression (LIMIT-D): Feasibility Study

Antidepressants are widely used as first-line treatments for major depressive disorder (MDD). Clinical guidelines recommend 6-24 months of "maintenance" antidepressant treatment, after patients achieve symptom remission, to prevent relapse but many people stop antidepressants too soon relapse into another depressive episode. We will test non-medication treatments, negative ion therapy and …

19 - 65 years of age All Phase N/A
K Keyla Ordonez, BS

Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression

This project will evaluate a telemedicine-delivered, Unified Protocol for Cognitive-Behavioral Therapy (UP-CBT) enhanced with continuous glucose monitor (CGM) review to target anxiety and depressive symptoms and glycemic control in adults with type 1 diabetes.

18 - 64 years of age All Phase N/A
D David Edelman, MD MHS

A New Intervention to Improve Function in Veterans With Anxiety and Depression

Anxiety and depression symptoms occur at high rates in Veteran populations and can significantly impact function, compromising the ability to work and to successfully form and maintain valued relationships. Several other symptoms commonly occur with anxiety and depression, including poor sleep quality and chronic pain. Since all these symptoms frequently …

18 - 65 years of age All Phase 2
M Mohamed Mamdouh Elsayed, MD

Effect of Intradialytic Exercise on Sleep, Depression and Anxiety in HD Patients

this study aims To assess the effect of intradialytic exercise program on sleep quality, depression and anxiety in HD Patients.

18 years of age All Phase N/A
T Temesgen Mekonnen

Salutogenesis and Self-efficacy-based Childbirth Education Programme for Preventing Postpartum Depression

Although the transition to motherhood is often a joyful experience, there is evidence that teenage motherhood can present many stressful challenges, potentially leading to the development of postpartum depression. Postpartum depression (PPD) remains a public health issue with negative consequences for both mothers and their babies. The aim of this …

13 - 19 years of age Female Phase N/A
R Roaa A. Alkreadees, MS

Effect of Probiotics "Psychobiotics" on Depression and Metabolic Syndrome in Saudi Arabia

The goal of this clinical trial is to assess the effect of commercial multi-strains psychobiotics supplementation as an ad-on therapy on depressive symptoms and metabolic syndrome components (HDL-C, FPG, TGs, WC, BP) in adult depressed patients with pre-metabolic syndrome and metabolic syndrome. The second goal is to explore the effect …

18 - 65 years of age All Phase 2/3
M Markus Björnström

A Metacognitive Group Therapy of Depression and Anxiety in Youth With Autism

This study is a single-center micro-randomized trial, aiming to examine the effects of two theory-driven reminder strategies on adherence to repeated, image-based meal logging in adults age 45 and older. Three times daily, participants are automatically randomized to receive one of three reminder messages prior to each habitual mealtime. The …

15 - 18 years of age All Phase N/A
C Chris Gregory, PhD

Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking

Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in individuals with post-stroke depression (PSD). Investigators propose to determine the efficacy of combining two known anti-depressant treatments shown …

21 - 70 years of age All Phase N/A

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