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Head and Neck Cancer Clinical Trials

A listing of Head and Neck Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 707 clinical trials

Retrospective Review of Esophageal Cancer at MSKCC

Residual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the investigators sought to evaluate the prognostic significance of the CRM in …

18 years of age All Phase N/A
Y Yuwei Qui, MD

Total Intravenous Anesthesia and Recurrence Free Survival

The investigators propose to compare recurrence-free survival in patients having potentially curative (Stages 1-3) surgery for esophageal cancer who will be randomly assigned to propofol-based total intravenous anesthesia or sevoflurane-based balanced general anesthesia.

18 - 90 years of age All Phase 3
B Bin Li, MD

Incidence of 106TBL Lymph Node Metastasis

the study was to document the incidence of left tracheobronchial lymph node metastasis, and the risk factors of metastasis.

20 - 85 years of age All Phase N/A
C Chen Haiquan, MD

Incidence of 107 Lymph Node Metastasis

the study was to document the incidence o subcarinal lymph node metastasis, and the risk factors of metastasis.

20 - 85 years of age All Phase N/A
J Jang-Ming Lee

ALDH2 Single Nucleotide Polymorphisms and Prognosis of Esophageal Cancer Patients

Alcohol consumption, smoking, and betel nut chewing have been proven to be closely associated with the risk of esophageal cancer (EC). Recent studies have shown that alcohol-related detoxification genes in the ALDH family influence individual susceptibility to esophageal cancer. Aldehyde dehydrogenase 2 (ALDH2) is one of the most important enzymes …

18 - 99 years of age Male Phase N/A

Perioperative SDD to Prevent Infectious Complications After Esophagectomy

The primary aim of the PERSuaDER-trial is to evaluate the effect of SDD on infectious complications after esophagectomy, focussed on the prevention of pneumonia

18 years of age All Phase 3
K Kuaile Zhao

Precision Palliative Care for Patients With Advanced Esophageal Cancer

The goal of this clinical trial is to learn if precision palliative care improves survival of patients with advanced esophageal cancer in adults. Researchers will compare precision palliative care and standard palliative care to see if precision palliative care works more effectively to treat advanced esophageal s cancer. Participants will …

18 years of age All Phase N/A
S Shu Peng, doctor

Integrating Multimodal AI to Predict Treatment Response and Refine Risk Stratification in Esophageal Cancer (Radiogenomics-Esophagus)

This AI-driven model leverages multimodal data-such as radiomics, pathomics, genomics, and broader multi-omics profiles-to capture complementary aspects of tumor biology and predict treatment response and prognosis.

years of age All Phase N/A

Treatment Outcomes of Esophageal Cancer

This study will be a carried out through a prospective observational cohort design in conjunction with researchers in the African Esophageal Cancer Consortium (AfrECC). The purpose of this research is to prospectively evaluate outcomes related to existing treatment strategies for esophageal cancer (EC) at participating sites within AfrECC.

18 years of age All Phase N/A
J Julie A. Ward, BSN

Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life

To assess short and long term outcomes after minimally invasive esophagectomy compared to open esophagectomy. To compare both standard outcome measures as well as patient derived outcome measures, in particular, quality of life (QOL). To look at the applicability of this QOL instrument to this patient group.

18 years of age All Phase N/A

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