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atrial-fibrillation Clinical Trials

A listing of atrial-fibrillation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 496 clinical trials
S Saman Nazarian, MD, PhD

Prospective Evaluation of CT Guided Ablation of Cardiac Ganglionated Plexi

Despite progress made in treating atrial fibrillation with catheter ablation, outcomes remain suboptimal with pulmonary vein isolation alone. Ablation of ganglionated plexi (GP) has been shown to be beneficial in patients with atrial fibrillation although optimal strategies of localization of these regions have yet to be determined. The investigators aim …

18 - 100 years of age Both Phase N/A
M Matevž Jan, MD

Endocardial Mapping of Left Atrium for Evaluation of Concomitant Surgical Ablation Lesions

Concomitant ablation is an effective treatment for patients with various types of atrial fibrillation undergoing heart surgery. However, recurrences of tachycardias after concomitant ablation can happen and seem to be mostly related to reentry mechanism resulting in atrial tachycardias. The aim of the study is to perform invasive re-mapping of …

18 - 80 years of age Both Phase N/A

Biomarkers in Pulsed Field Ablation Versus Cryoballoon Ablation

Our study will include consecutive patients undergoing pulsed field ablation (PFA) or cryoballoon (CBA) ablation. Tissue injury and inflammation markers will be measured before and after the procedure.

18 - 75 years of age Both Phase N/A
D Dr. Keng Tat Koh, MBBS

Left Atrial Appendage Occlusion With The Amplatzer Amulet Device: The Southeast Asia Observational Study

This is a prospective and retrospective, multicenter observational study where the study is being performed to explore on the short-term and long-term safety and efficacy of LAA occlusion with Amplatzer Amulet Device in Southeast Asia population on a real-world basis.

18 - 100 years of age Both Phase N/A
T Toral Odedra

An Investigator-initiated Linked Study to OCEANIC-AF

Impaired endogenous fibrinolysis is a recently recognised risk factor for thrombotic events in patients with cardiovascular disease. Enhancing endogenous fibrinolysis in such individuals represents a way of reducing thrombosis risk. However, the optimal pharmacotherapy to enhance fibrinolysis is unclear. The aim of this study is to assess the effect of …

18 - 100 years of age Both Phase N/A
R Ravi Ranjan, MD

Prospective Study to Validate Ablation Parameters With MRI Based Scar for Left Atrial Ablation

One of the goals of an ablation procedure is to create scarring of cardiac tissue. Not all ablations result in scar tissue. Advances in technology have improved scarring but ideal parameters that result in scar tissue are still not completely clear and there is great variability in the parameters used. …

18 - 100 years of age Both Phase N/A
P Pavel Osmancik, MD,Ph.D.

Heart Rate Variability After Ablation

Pulsed-field catheter ablation is a promising new treatment method for patients with atrial fibrillation. The mechanism of cell damage here is different from that of classic catheter ablation, in which the ganglion plexuses around the pulmonary veins are also damaged and thus changes in the autonomic nervous system occur. The …

18 - 75 years of age Both Phase N/A
D Donita Atkins

Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation

Observational, multi-center, clinical device registry for US patients with a primary goal to observe the clinical outcomes in patients who are mapped with Volta Medical's VX1 or AF-Explorer systems during AF ablation procedures.

21 - 100 years of age Both Phase N/A
C Charles-Henri DAVID

Interest of a Hybrid Connected Watch for Cardiac Rhythm Monitoring in Post-operative Cardiac Surgery

The objective of this single-center pilot study is, with the help of a connected watch, to show the absence of recurrence or maintenance of sinus rhythm in patients with a Post Operative Atrial Fibrillation (POAF) and to help treating cardiologists in the care of these patients.

18 - 100 years of age Both Phase N/A
F Francisco Manuel Martin Lujan, Medicine

Diagnostic Approach of Early Atrial Fibrillation, Silent Stroke and Cognitive Disorder in Patients With High-risk

The goal of this observational study is to determine the impact of the combined use of cardiac rhythm recording devices, biomarkers, echocardiogram, and Magnetic Resonance Imaging (MRI) on the early detection of AF, silent stroke, and cognitive impairment in subjects older than 65 years at high risk. The main questions …

65 - 85 years of age Both Phase N/A

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