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atrial-fibrillation Clinical Trials

A listing of atrial-fibrillation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 473 clinical trials
C CHIN-YU LIN

Waveform Periodicity Analysis in Patients With Persistent Atrial Fibrillation

STUDY DESIGN A prospective study. OBJECTIVE A single center clinical trial on the analysis of intracardiac atrial electrogram waveform periodicity for catheter ablation of persistent atrial fibrillation with OCTARAY™ Mapping Catheter, as prospective randomized controlled study. HYPOTHESIS The critical atrial substrates in maintaining persistent atrial fibrillation could be identified by …

20 - 80 years of age All Phase N/A
D Darren Hooks, MBChB, PhD

Shock Energy for Electrical Cardioversion of Persistent Atrial Fibrillation

The goal of this clinical trial is to compare the efficacy of a maximum output shock for cardioverting atrial fibrillation between two commonly used defibrillators in New Zealand . These machines have different maximum energy outputs, and to date no head-to-head comparison cardioverting atrial fibrillation between the two has been …

18 years of age All Phase N/A
J Jose Osorio

A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects with PAF:

The objective of this clinical study is to demonstrate that ablation with the TactiFlex SE Ablation catheter, in conjunction with a compatible pulsed field ablation (PFA) and/or radio frequency (RF) generator, is safe and effective for the treatment of symptomatic, recurrent, drug refractory paroxysmal atrial fibrillation (PAF).

18 years of age All Phase N/A

Ablation Strategies for Persistent Atrial Fibrillation Combined With Heart Failure

(1) To evaluate the efficacy and safety of "2C3L" strategy combined with VOM anhydrous ethanol chemical ablation for persistent atrial fibrillation complicated with heart failure; (2) To evaluate the effectiveness of high-efficiency ablation of atrial fibrillation complicated with heart failure.

18 - 80 years of age All Phase N/A
M Mu Qin

Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation

The design of this study is an intervention, randomized, controlled study and contains three randomized groups:(1)PVI group;(2)PVI+PWI group;(3)PVI+PWI+EGM group.

18 - 80 years of age All Phase N/A
N Nicasio Pérez-Castellano, MDhPhD

Value of Screening and Treatment of SAHS in the Management of AF Ablation Candidates

The present prospective cohort study (not randomized) analyses the value of screening and treatment of SAHS in the management of patients with AF refractory to antiarrhythmics drugs, potentially candidates for ablation. Patients at low risk of suffering from SAHS will follow conventional management of their AF, according to the usual …

18 years of age All Phase N/A
C Chunyu Yu, MD

LAA Clipping Versus NOACs to Prevent Stroke in Non-paroxysmal Atrial Fibrillation.

This trial is designed to examine the hypothesis that thoracoscopic LAA clipping is superior to NOACs for stroke, systemic embolism, all-cause mortality, major bleeding events and clinically relevant nonmajor bleeding events in AF patients at high risk of embolism (CHA2DS2-VASc ≥2 in men and ≥3 in women) that are not …

18 years of age All Phase N/A

Safety and Performance of the SpherePVI™ Catheter to Treat Paroxysmal Atrial Fibrillation

A prospective, single-arm, single-center study to evaluate the safety, performance, and effectiveness of the SpherePVI™ Catheter for treating paroxysmal AF.

18 - 75 years of age All Phase N/A
P Piotr Futyma, MD, PhD

Pulsed Field Ablation With Concomitant Radiofrequency Cardioneuroablation in Patients With Paroxysmal Atrial Fibrillation

Pulsed-field ablation (PFA) is a novel, non-thermal method for the treatment of atrial fibrillation (AF). It uses short, high-voltage electrical pulses to selectively ablate cardiomyocytes. PFA has demonstrated a high safety profile with reduced complication rates compared to thermal ablation. Thermal ablation of parasympathetic ganglia during conventional pulmonary vein isolation …

18 years of age All Phase N/A
L Laia Hernández

PLAI-AF Trial: Hybrid Endo-epicardial Partial Left Atrial Isolation vs. Endocardial Ablation in Patients With Persistent Atrial Fibrillation

In patients with symptomatic atrial fibrillation (AF), current clinical guidelines recommend ablation for rhythm control. While percutaneous ablation has good results in patients with paroxysmal AF, it is not clear which is the best technique in patients with persistent or long-standing persistent AF. Our group performed the first randomized study …

18 - 75 years of age All Phase 3

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