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Traumatic Brain Injury Clinical Trials

A listing of Traumatic Brain Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 271 clinical trials
E Evan Gu

A Study to Evaluate the SENSE Device's Ability to Detect TBI

The study population will consist of 3 mutually-exclusive sets of patients and subjects: TBI patients with intracranial bleeding TBI patients without intracranial bleeding Control subjects with normal brain health. Research subjects ages 22 and older will be enrolled. All TBI patients must be monitored with the SENSE Device within 6 …

22 years of age All Phase N/A
C Casey S Gilmore, PhD

Remote Stimulation and Training to Advance Recovery From TBI in Seniors

The goal of this clinical trial is to learn if combining brain stimulation with cognitive training can improve thinking skills in older adults who have had a traumatic brain injury (TBI). The main questions are: Does transcranial direct current stimulation (tDCS) make cognitive training more effective for improving attention, memory, …

65 years of age All Phase N/A
R Ronda A Ronda PETREY

Hyperbaric Oxygen Brain Injury Treatment Trial

The purpose of this innovative adaptive phase II trial design is to determine the optimal combination of hyperbaric oxygen treatment parameters that is most likely to demonstrate improvement in the outcome of severe TBI patients in a subsequent phase III trial.

16 - 65 years of age All Phase 2
M Mariela Aguilar, PhD

Understanding and Treating Traumatic Brain Injury (TBI) Associated Photophobia With Botulinum Toxin Type A (BoNT-A)

The purpose of this research is to understand and treat Traumatic Brain Injury (TBI) associated photophobia (light sensitivity) and its impact on visual function.

18 years of age All Phase 2

The REACH Intervention for Caregivers of Veterans and Service Members With TBI

This randomized waitlist control trial will evaluate the effects of a psychoeducational intervention called Resources for Enhancing All Caregivers' Health - Traumatic Brain Injury (REACH TBI) to decrease caregiver strain (primary outcome) and improve caregiver self-efficacy, anxiety, depression, and health care frustrations (secondary outcomes). This study will modify and adapt …

18 years of age All Phase N/A
E Emerald Saldyt

University of Colorado - Restoring Efficient Sleep After TBI

Sleep disturbance is a common condition following traumatic brain injury (TBI) and impairs recovery and quality of life. While efficacious interventions exist many are not accessible to all patients due to a variety of factors (e.g., rurality, access to providers). Further, many of the available treatments have not been validated …

18 - 60 years of age All Phase N/A
H Hisao Yean Chiu, PhD

Effects of Nurse-Guided BBTi for Improving Insomnia : in Patients at the Recovery Following Traumatic Brain Injury

nsomnia is a frequent complaint reported by patients with TBI, and exacerbates their ability to return to productive activity, which subsequently elevate related healthcare costs and burden. Existing literatures found that effects of CBTi, first-line therapy for insomnia, on post-traumatic insomnia is still debated, indicating that developing an alternative nonpharmacological …

20 - 65 years of age All Phase N/A
R Rosy Njonkou Tchoquessi

Hyperpolarized 13C-pyruvate Metabolic MRI With Traumatic Brain Injury

The purpose of this study is to examine the safety and feasibility of using hyperpolarized metabolic MRI to study early brain metabolism changes in subjects presenting with head injury and suspected non-penetrating traumatic brain injury (TBI). This study will also compare HP pyruvate MRI-derived metrics in TBI patients with healthy …

18 - 80 years of age All Phase 1
M Maria Kajankova, PhD

Community-based Implementation of Online EmReg

This is a hybrid type III implementation-effectiveness trial; this study design blends elements of implementation and clinical effectiveness research, with the primary aim of determining the utility of an implementation strategy and a secondary aim of assessing clinical outcomes associated with the implementation trial. Consistent with best practices for this …

18 years of age All Phase N/A

Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury

The goal of this blinded, adaptive, randomized, placebo-controlled clinical trial is to investigate the use of hyperbaric oxygen as a therapy to treat mild to moderate traumatic brain injury in Veterans and active military. The main questions it aims to answer are: Does Hyperbaric Oxygen Therapy (HBOT) reduce neurobehavioral symptoms? …

18 - 75 years of age All Phase 3

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