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neuropathy Clinical Trials

A listing of neuropathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 434 clinical trials
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Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

This phase III trial compares the effect of 3 study approaches in preventing chemotherapy-induced peripheral neuropathy: 1) cryocompression, 2) continuous compression, and 3) low cyclic compression. Taxane chemotherapy drugs, such as paclitaxel or docetaxel, can cause a nerve disorder called peripheral neuropathy, which can cause numbness, tingling, or pain in …

18 years of age All Phase 3
D Daniele Mautone, MD

Collection of Demographic, Clinical, and Instrumental Data of Patients With Peripheral Neuropathy Including Neurological Examination Data, Peripheral Nerve Conduction Analysis, and Nerve Electromyography and Ultrasound).

The study involves recording personal, clinical, and instrumental information. The acquisition of the above-mentioned personal and clinical information will be carried out in conjunction with the usual follow-up visits scheduled as part of normal clinical practice. At the end of the study, a statistical analysis of the data will be …

18 years of age All Phase N/A

Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

The purpose of this study is to collect and evaluate pregnancy outcomes, pregnancy complications, and fetal/neonatal/infant outcomes in women exposed to patisiran-LNP.

years of age Female Phase N/A
B Britt S Pedersen

Polyneuropathy, Impairments and Physical Activity - The PolyImPAct Study

The project aims to investigate the validity, and reliability of outcome measures of muscle strength, functioning (gait, balance, and fine motor skills), physical activity, and patient-reported outcome measures of functioning (gait, balance, and fine motor skills), and daily living among patients with polyneuropathy. Further, the project aims to compare physical …

18 - 100 years of age All Phase N/A
K Katrin Dillmann

Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related Disorders

The aim of this study is to determine the clinical spectrum and natural progression of Hereditary Spastic Paraplegias (HSP) and related disorders in a prospective multicenter natural history study, identify digital, imaging and molecular biomarkers that can assist in diagnosis and therapy development and study the genetic etiology and molecular …

years of age All Phase N/A
D Damien Dauphinee, DPM

Continuous Observational Monitoring Program for Allay™ Hydrogel Cap Safety and Success Study

is is a multi-center, open-label, observational registry study (both prospective and retrospective) designed to evaluate the safety and performance of the allay™ Hydrogel Cap. This cap is an in situ forming implantable hydrogel medical device used in various peripheral nerve surgeries, including amputation and neuroma excision. The study aims to …

years of age All Phase N/A
S Shawna Feely, MC, GC

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.

years of age All Phase N/A
D Darius Ebrahimi-Fakhari, MD, PhD

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biological samples (skin and/or blood and/or saliva) from male and female patients, under the age of 30, who exhibited early onset symptoms of HSP with (1) a …

- 30 years of age All Phase N/A
M Maria E Denbow

Establishing Normative Data for Pupillometer Assessments in Neuro-Intensive Care

The purpose of this study is to collect a large amount of data that may assist in addressing the gap in knowledge of understanding pupillometer readings using a pupillometer device. The aim of this project is to establish normative values for pupillometer data. Measures of central tendency will be developed …

years of age All Phase N/A
J Ji Hyun Lee, MD., Ph.D.

International CIPN Assessment and Validation Study

This is an observational study of chemotherapy-induced peripheral neurotoxicity (CIPN) patients to be investigated prospectively in order to assess responsiveness of a set of outcome measures in an international multi-center study.

18 years of age All Phase N/A

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