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neuropathy Clinical Trials

A listing of neuropathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 409 clinical trials
S Sven Mularski, Dr.med.

Post Market Clinical Follow up Study With the Cervical Disc Prothesis MOVE®-C

Study design: International, prospective, multicentre, non-randomised, observational study according to § 23b MPG. Objectives: Observational study to confirm the safety and performance of the cervical disc prosthesis MOVE®-C.

18 years of age All Phase N/A
L Lori Backus

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

Plexiform neurofibromas (PN) are known to cause significant morbidity in children with NF1. The recent FDA approval for selumetinib in children 2 years and older with inoperable symptomatic PN was based on the finding that selumetinib shrinks the majority of PN in children with NF1 and results in clinically meaningful …

1 - 8 years of age All Phase 2
A Andra EZARU

Evaluation of Urinary Dysfunction in CANVAS Patients

The investigator wishes to evaluate the prevalence of urinary symptoms in patients diagnosed with Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS). As much as one third of patients living with CANVAS experience symptoms of urinary system dysfunction. The primary objective of this study is to evaluate the incidence of urinary …

18 years of age All Phase N/A
R Roslyn M Kackman

Closed Loop Spinal Cord Stimulation for Complex Regional Pain Syndrome

The primary purpose of this study is to determine the differences in response to treatment of complex regional pain syndrome with a closed-loop spinal cord stimulator if applied in the early phases (acute or subacute) versus the chronic phase.

18 years of age All Phase N/A
E Eva Widerstrom-Noga, PhD

Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI

The main purposes of this study are to (1) measure the effect of CBD/CBD-A on pain symptoms, pain intensity, pain unpleasantness, and skin sensitivity to hot and cold temperatures; and (2) measure the effect of CBD on brain electrical activity with electroencephalography (EEG).

18 - 64 years of age All Phase 1/2
N Nina L Gehr, MD

Prevention of Oxaliplatin-induced Nerve Damage in the Body's Extremities

The purpose of this study is to examine the effect of supplementary polyunsaturated fatty acids on nerve damage in the body's extremitites of patients treated with oxaliplatin containing chemotherapy after surgery for colorectal cancer.

18 years of age All Phase N/A
A Anuj Bhatia, MD FRCPC

Mechanisms and Outcome-Prognostication for Paresthesia-based and -Free Spinal Cord Stimulation

Spinal cord stimulation (SCS) relies on stimulation of pain-relieving pathways in the spinal cord to treat chronic neuropathic pain. Traditional paresthesia-based SCS (PB-SCS) relies on providing analgesia through stimulation of spinal cord dorsal columns but it is often associated with attenuation of analgesic benefit and lack of acceptance of paresthesias. …

18 - 80 years of age All Phase N/A
A Andreas Nowacki, MD

Thalamic-Burst-DBS for Neuropathic Pain

Central post-stroke pain (CPSP) is a neuropathic pain syndrome and one of the major sequelae after ischemic or hemorrhagic cerebral stroke. Recently, a modified stimulation paradigm has been developed in the field of spinal cord stimulation (SCS) for a variety of neuropathic pain disorders. To date, this stimulation paradigm has …

18 - 75 years of age All Phase N/A
Z Zak Sturgill

Insula Neuromodulation for Chronic Neuropathic Pain

This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.

18 - 80 years of age All Phase N/A
M Mathilde Scholtes, MSc

Spinal Cord Stimulation for Intractable Mononeuropathy

Rationale: For patients with mononeuropathy, literature has shown that spinal cord stimulation (SCS) is an effective therapy for patients who are therapy-resistant to more conventional treatments. However, there is a strong need for higher quality evidence to determine the place of this therapy in this target group. Before conducting a …

18 years of age All Phase N/A

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