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ovarian-cysts Clinical Trials

A listing of ovarian-cysts medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 74 clinical trials
Z Zhengwei Wan

Mechanism of Red Yeast Rice Regulating Intestinal Indole Metabolism Pathway to Improve Chronic Inflammation in Polycystic Ovary Syndrome

The aim of this study is to elucidate the effects of red yeast rice on the improvement of symptoms in patients with polycystic ovary syndrome(PCOS), and to analyze the dose-response relationship between intestinal microbiota and its metabolite, hydroxyindole, and clinical indicators of PCOS. The main questions it aims to answer …

18 - 40 years of age Female Phase N/A
M Mohamed Adel Mousa, Resident

Combination Letrozole and Clomiphene Citrate Versus Letrozole Alone

Clomiphene citrate is a non-steroidal triphenylethylene derivative distantly related to diethylstilbestrol. It acts as a selective estrogen receptor modulator (SERM), similar to tamoxifen and raloxifene. All three drugs are competitive inhibitors of estrogen binding to estrogen receptors (ERs) and have mixed agonist and antagonist activity, depending upon the target tissue. …

20 - 35 years of age Female Phase N/A
J JINGJING JIANG, MD

Efficacy of Mazdutide for Treating PCOS

The goal of this clinical trial is to learn the efficacy of Mazdutide in treating obese female adults diagnosed with polycystic ovary syndrome (PCOS). The main question it aims to answer is: Does Mazdutide lower the free androgen index (FAI) in obese female adults with PCOS? Participants will take Mazdutide …

18 - 40 years of age Female Phase 1/2
R Rukhsana Shaheen, MBBS, FCPS

Comparison of Clomid and Lezra With Lezra for Ovulation Induction in Clomid Resistant PCOS Case

Clomiphene citrate resistant i.e failure to ovulate after 6 cycles of ovulation induction effects 15-40% of patients with PCOS.Two treatment groups will be formed one recieving letrozole alone and another recieving CC and letrozole combined.Mature follicles and endometrial thickness will be checked by transvaginal ultrasound and results will be recorded.

20 - 40 years of age Female Phase 1
J Jamie I Baum, PhD

Protein and Polycystic Ovary Syndrome (PCOS)

Polycystic ovary syndrome (PCOS) is a significant public health problem and is one of the most common hormonal disturbances affecting women of reproductive age. Women with PCOS are often insulin resistant, increasing their risk for cardiometabolic health problems (e.g., type 2 diabetes, heart disease, high blood pressure, sleep apnea, anxiety, …

18 - 50 years of age Female Phase N/A

The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients

The study aims to evaluate the effects of combination of metformin with NAC in PCOS on biochemical and hormonal parameters.

20 - 45 years of age Female Phase 3
J Jamie I Baum, PhD

Appetite Response to Meals With Different Protein Sources in Women With PCOS

Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by insulin resistance, hyperandrogenism, and reproductive dysfunction. Dietary strategies that improve postprandial insulin and glucose responses are central to managing metabolic symptoms in PCOS. Meals higher in protein can attenuate postprandial glycemia and enhance satiety, but the effects may vary …

18 - 50 years of age Female Phase N/A
J Jie Qiao

Sitagliptin or BeiDouGen Capsule Improve the Pregnancy Outcome in Patients with PCOS

This study will be carried out under the guidance of professional doctor, patients with PCOS will be treated with Sitagliptin or BeiDouGen capsule or both two to assess their ovarian function and reproductive outcomes, and compare the effect of different treatment methods, which will provide the basis for PCOS intervention …

20 - 40 years of age Female Phase N/A
J Jaana E Nevalainen, Assoc Prof

Strengthening Healthy Emotional Co-regulation of Mothers With PCOS and Obesity and Their Infants

It is both timely and important to invest in interventions that can improve healthy emotional co-regulation. It is proposed to evaluate the feasibility and limited efficacy of an adapted, brief, multimodal intervention: ECoFam (Emotional connection and Co-regulation for Families). Evidence from the US suggests intervention effects on maternal and infant …

years of age Female Phase N/A

Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome

In PCOS (Polycystic Ovary Syndrome), studies have found impaired incretin secretion and activity, particularly in overweight/obese individuals. Conflicting results exist regarding glucagon-like peptide-1(GLP-1) levels in PCOS patients, with studies reporting reduced, normal, or increased levels. Incretin-based therapy has been suggested as a potential treatment to reverse prediabetes risk by preserving …

18 - 40 years of age Female Phase 3

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