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Seizure Disorders Clinical Trials

A listing of Seizure Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 321 clinical trials

The Clinical Utility of BioEP in Diagnostic Decision Making in Epilepsy

Neuronostics plan a prospective multisite trial to determine the clinical utility of BioEP in the context of diagnostic decision making. Neuronostics will use findings from the trial to improve user experience of the Neuronostics platform (the tool which clinicians use to obtain a BioEP score from EEG and the aligned …

18 years of age All Phase N/A
L Lilian Lusimbo

Bridging the Treatment Gap by Expanding Access to Care for People With Epilepsy in Kenya (BEACON)

This cluster randomized trial aims to learn about the effectiveness of task-sharing supported by an epilepsy medical records system (EMRS) (hereafter referred to as BEACON) with patient-tracking data in improving treatment adherence and retention in care in people with epilepsy in western Kenya.

12 years of age All Phase N/A

Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

Objectives The overall study objective is to compare the sensitivities and specificities of morphometric analysis techniques using structural MRI images based on pre- and postsurgical localization of epileptic foci in patients undergoing presurgical evaluation for medically refractory epilepsy. To carry out these analyses, we aim to establish an age-stratified normative …

8 - 120 years of age All Phase N/A
S Saskia Semmlack, Dr. med

Status Epilepticus Population Study (STEPS)

The aim of this observational multicenter cohort study is to gain a deeper understanding regarding the effects of treatment adaption based on information from outcome prediction models, risk stratification, as well as treatment monitoring, detection, prevention, and management of complications on course and outcome of adult patients with status epilepticus …

18 years of age All Phase N/A
G Gitte M Knudsen, DMSc

Precision Medicine in the Treatment of Epilepsy

Primary objectives: The purpose of this study is to identify single and composite biomarkers (from neuroimaging, electrophysiological, and non-imaging biological measures), clinical measures (from cognitive, psychometric, and behavioral test scores), and risk/protective factors (e.g., from medical history, socioeconomic status, coping, lifestyle) that can: Predict antiseizure medication (ASM) treatment outcome, psychiatric, …

16 - 55 years of age All Phase N/A
L Lena Habermehl, MD

Effect of the New Definition of Epilepsies of the ILAE of 2014 on the Diagnosis After the First Seizure

The present study is a prospective study on the development of seizure frequency, medication adherence, quality of life and cognitive performance after a first epileptic seizure using the new diagnostic criteria for epilepsy of the International League Against Epilepsy of 2014 at the time of diagnosis.

18 years of age All Phase N/A
S Sigrid Bjuresäter, Registered nurse

EPIGUT: EPILEPSY AND GASTROINTESTINAL MICROBIOTA: UNDERSTANDING THERAPY RESPONSE

The goal of this observational study is to learn how the bacteria in the gut and mouth (called the microbiota) are linked to different types of epilepsy and how they may affect how well seizure medicines work. Researchers want to answer two main questions: Are certain types of epilepsy linked …

2 - 79 years of age All Phase N/A
F Frédéric Villéga, Dr

Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents

Rare epilepsies as a whole account for 20-30% of epilepsies, but knowledge about prognostic factors is currently limited. This means that it is difficult to provide adequate information to families at diagnosis and during follow-up. Prognostic factors are also important for management as they can have an impact on the …

- 15 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Investigating Epilepsy: Screening and Evaluation

Background Epilepsy affects about 1 percent of the U.S. population. Most people with epilepsy respond well to medicine, but some do not. Researchers want people who have diagnosed or suspected epilepsy to participate in ongoing studies. They want to learn more about clinical care for epilepsy. They want fellows and …

8 - 110 years of age All Phase N/A
R Rebecca Brito

De-identified UNMH EEG Corpus Database Creation With Fully De-identified Clinical Information

This proposal outlines the steps required for the creation of a pilot database of EEG recordings and de-identified medical records from patients internally referred within the UNMH Comprehensive Epilepsy Center. The UNMH EEG Corpus would be the first database of its kind. Other public databases contain either patient EEG signals …

18 years of age All Phase N/A

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