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Sarcoma Clinical Trials

A listing of Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 164 clinical trials
N Nandini Rajgopal, BS

Healthy Lifestyles in Bipolar Disorder: Bay Area Study

The goal of this clinical trial is to understand how level of adherence with time-restricted eating (TRE) predicts change in diurnal rhythms (as measured using the amplitude of diurnal peripheral clock gene expression), and how those changes predict lower mania and depressive symptoms, and downstream improvements in quality of life. …

18 - 65 years of age All Phase N/A
L Lars V Kessing, Professor

Lithium Versus Lamotrigine in Bipolar Disorder, Type II

The investigators want in a 6-month randomized controlled trial (RCT) to compare effects of lithium versus lamotrigine on mood stabilization and other critical patient outcomes in patients with BDII.

18 - 70 years of age All Phase 4
M Marcus Gabrielsen, Cand.med.

The PEDAL Intervention - Reducing Affective Lability in Bipolar Disorder

PEDAL is a group-based intervention for patients with bipolar disorder that builds on the traditional group psychoeducational program (GPP) by adding digital tools and specific strategies to help manage rapid fluctuations between affective states, known as affective lability. The program's goal is to help patients learn and develop new ways …

18 - 65 years of age All Phase 2
K Katherine Scangos, MD, PhD

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

Neurons are specialized types of cells that are responsible for carrying out the functions of the brain. Neurons communicate with electrical signals. In diseases such as major depression this electrical communication can go awry. One way to change brain function is using electrical stimulation to help alter the communication between …

22 - 70 years of age All Phase N/A
D Dost Ongur, MD PhD

Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder

The goal of this clinical trial is to test how specific components of diet affect brain function and behavior for individuals with bipolar. The main question it aims to answer is how glucose and ketones each affect the brain's response to risk and reward. Participants will be asked to provide …

18 - 45 years of age All Phase N/A
O Oluwatofunmi Olaniyan

A Study of Home-use Brain Stimulation to Treat Bipolar Depression

Bipolar depression is a long-lasting and disabling condition, and many people continue to experience depressive symptoms despite standard treatments. Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation that uses a very small electrical current applied through the scalp and has shown promise as a treatment for …

18 years of age All Phase N/A
M Mawahib Semeralul

Low Frequency Right Dorsolateral Pre Frontal Cortical Repetitive TMS for Bipolar Depression

The purpose of this trial is to conduct an adequately powered clinical trial of once daily LFR for individuals diagnosed with treatment-resistant BD-DE who have not responded to iTBS or sham treatment applied to the left DLPFC. This work will develop the evidence supporting the use of LFR rTMS for …

18 years of age All Phase 3
Y Yvette Sheline, MD, MS

Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder

The objective of this study protocol is to test whether intermittent theta-burst transcranial magnetic stimulation (iTBS-TMS) to the inferior parietal lobule (IPL) can strengthen functional connectivity with a key region in emotion regulation (ER) neurocircuitry (anterior insula, AI) and improve performance on ER-related tasks in patients with bipolar disorder. Individual …

24 - 65 years of age All Phase N/A
J Joshua P Nixon, PhD

mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders

Veterans with bipolar disorders (BD) experience recurrent and seemingly unpredictable periods of severe impairments in psychosocial functioning, such as participation in social roles and activities. Many effective treatments for BD emphasize early detection of bipolar episodes, in order to make necessary treatment adjustments and prevent psychosocial impairments associated with acute …

18 years of age All Phase N/A
R Rosemary Smith, B.S.

Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder

Preliminary data have suggested that cannabidiol (CBD) may have a number of clinical benefits, including anti-anxiety and antidepressant properties. This study is a pilot open-label clinical trial assessing a custom-formulated high-CBD product over the course of 4 weeks in patients with bipolar disorder who experience anxiety.

18 - 65 years of age All Phase 2

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