Advanced Filters
noise

Rheumatoid Arthritis Clinical Trials

A listing of Rheumatoid Arthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 277 clinical trials
S Shrouk Ali, M.Sc

Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a long-term inflammatory condition that leads to gradual damage of joints lined by synovial membranes, along with various potential effects outside of the joints. While RA can affect any joint, it typically involves the metacarpophalangeal, proximal interphalangeal, and metatarsophalangeal joints, as well as the wrists and …

18 - 70 years of age All Phase 2
B Bruno FAUTREL, MD

Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis

As stated by the European League Against Rheumatism (EULAR) and the Société Française de Rhumatologie (SFR), treatment of patients with rheumatoid arthritis (RA) should target sustained remission or at least low disease activity. However, despite significant advances based on various combinations of conventional synthetic disease-modifying antirheumatic drugs (DMARDs) and biologic …

18 - 65 years of age All Phase 3
F Femke Hooijberg, MD

Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring

Several prior studies have shown that dose reduction of Tumor Necrosis Factor (TNF)-inhibitors like adalimumab is possible in substantial number of rheumatic disease patients without an increase in disease activity. Biologic therapy is expensive, and is associated with patient burden as dose dependant risk for serious infections . A dose …

18 years of age All Phase 4
A Abdallah A Eldisouky

L-carnitine in Modulating Pain and Inflammation in Rheumatoid Arthritis

This study aims at evaluating the possible efficacy and safety of L-carnitine in rheumatoid arthritis via targeting Jak/STAT pathway and TGF-β1

18 - 70 years of age All Phase 3

Post-marketing Re-evaluation of WangBi Granules for Rheumatoid Arthritis

The group used a randomized controlled trial to conduct a post-marketing re-evaluation study of Wangbi granules. The study was conducted to observe the degree of clinical remission in rheumatoid arthritis patients with low disease activity after standard methotrexate and tofacitinib citrate treatment, using a combination of Chinese and Western medicine …

18 - 75 years of age All Phase 4

A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis

The aim of this study is to evaluate the safety of F8IL10 when administered by intra-articular injection and to determine the maximum tolerated dose (MTD) in order to establish the recommended dose (RD) in patients with Reumatoid Arthritis.

18 - 80 years of age All Phase 1
A Adicet Clinical Trials

A Phase 1 Study of ADI-001 in Rheumatoid Arthritis

ADI-001-106 is a phase 1 study of ADI-001 with a randomized, single-blind, parallel group design to compare two different LD regimens in subjects with treatment-refractory RA. The study will consist of different periods including screening, LD, treatment, and follow-up

18 - 80 years of age All Phase 1
T Tanja Thomsen, Ph.D.

Feasibility Study: Plant Based Diet to Patients With Rheumatoid Arthritis

In this feasibility study, our primary goal is to assess the practicality of implementing a plant-based food diet intervention for individuals with rheumatoid arthritis (RA). The intervention consists of three key components: 1) Educational materials (videos), 2) Participation in a cooking workshop introducing plant-based meals, complete with recipes, and 3) …

18 years of age All Phase N/A
A Andreas Klein

Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis

This study will test the safety and effects of SBT777101 when given as a single dose to subjects with rheumatoid arthritis. It is the first study of this treatment being done in humans. Increasing dose levels will be given after the safety at lower dose levels is shown.

18 - 70 years of age All Phase 1

An Ascending Dose Study of PIT565 in Participants With Rheumatoid Arthritis

The purpose of the study is to determine the safety, tolerability, and pharmacokinetics of PIT565, in participants with rheumatoid arthritis (RA).

18 - 75 years of age All Phase 1

Simplify language using AI