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pregnancy Clinical Trials

A listing of pregnancy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 826 clinical trials
K Kelsey Schwartz

Vascular Effects of High-Salt After Preeclampsia

Women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life, even if they are otherwise healthy. Importantly, women who had preeclampsia have an exaggerated vascular responsiveness to hypertensive stimuli, such as high-salt intake, compared to women who had a healthy pregnancy. …

18 - 45 years of age Female Phase 0
H HUNG-HUI CHEN

The Project for Managing Cardiometabolic Risk in Women Diagnosed With Gestational Diabetes Mellitus

This study aims to examine the effects of a lifestyle intervention based on a health belief model (HBM) supported by mobile health (mHealth) and the impact of continuous glucose monitoring (CGM) on maternal glycemic parameters, cardiometabolic risk, health behavior and infant's outcomes among women diagnosed with gestational diabetes mellitus (GDM).

18 years of age Female Phase N/A
K Kadriye Yakut Yucel, MD

Fetal Fornix and Hippocampus in Pregnant Women With Early-Onset Preeclampsia

Since early-onset preeclampsia (EOPE) is commonly associated with inadequate placentation, placental insufficiency, chronic fetal hypoxia, oxidative stress, and heightened inflammation, these pathological processes may adversely affect hippocampal neuronal development and maturation of axonal pathways such as the fornix. These mechanisms support our hypothesis that fetal fornix and hippocampus dimensions may …

18 - 45 years of age Female Phase N/A
A Alexander Butwick

Ropivacaine and Fentanyl for Labor Epidural Initiation

This study is being done to determine the most effective dose of medicine to use to initially provide effective pain relief within the first 30 minutes of receiving an epidural for pain labor during labor. The study team will also study any side effects related to the epidural medication and …

18 years of age Female Phase 3
W Willis Barr

Antidepressant Therapy for Improved Blood Vessel Health After Preeclampsia

Preeclampsia is a condition in pregnancy where a woman develops high blood pressure and other complications. Women who develop preeclampsia are 4 times more likely to have heart disease later in life. They are also more likely to have depression after pregnancy. Why they are more likely to develop these …

18 - 45 years of age Female Phase 0

Maternal Methyl-Nutrient Status and Infant Neurodevelopment Study

This prospective cohort study examines the relationship between maternal methyl-nutrient status during pregnancy and offspring neurodevelopment. It integrates maternal dietary, biomarker, genetic, and microbiome data and follows children up to 24 months.

- 45 years of age All Phase N/A

Culturally Engaged REcovery: MOms Connected Through Native communitY

Pregnant and postpartum American Indian and Alaska Native people (Native mothers) face a more than two-fold higher risk of maternal mortality compared to non-Hispanic White mothers. Deaths related to substance use (SU) and mental health conditions are a leading cause of preventable maternal mortality, including among Native mothers, making these …

18 years of age Female Phase N/A
L Ling-Qun Hu, MD

Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight

This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia. It compares whether continuous noninvasive hemodynamic measurements from the lower extremity (toe) better predict neonatal outcomes than upper extremity (arm/finger) measurements during spinal-induced hypotension. Participants receive standard spinal anesthesia and routine blood …

18 years of age Female Phase N/A
T Tonko Mardesic, MD, PhD

Fertility Outcomes After Antibiotic Treatment In Women With Chronic Endometritis

Chronic endometritis (CE) is a long-lasting inflammation of the lining of the uterus. Many women with CE do not have symptoms, but the condition may affect fertility, embryo implantation, and pregnancy outcomes. CE is usually diagnosed during hysteroscopy, a procedure that allows doctors to look inside the uterus and collect …

18 - 40 years of age Female Phase N/A
C Cristina Palacio, MD

Organ Dysfunction Score for Obstetric Patients

The goal of this observational study is to develop and evaluate an organ dysfunction score adapted to pregnancy and early puerperium (SOFA-OBS) that also incorporates a non-invasive tool to evaluate respiratory function (pulse oximeter). The main question it aims to answer is: Does an organ dysfunction score adapted to pregnant …

18 years of age Female Phase N/A

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