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pregnancy Clinical Trials

A listing of pregnancy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 818 clinical trials
Y Yafei Wang, Master

Pregnancy Outcomes in Normotensive VS stage1 Hypertension: a Prospective Observational Study

In 2017, the American College of Cardiology (ACC) and American Heart Association (AHA) guidelines built on evidence that elevated blood pressure increases cardiovascular mortality in the general population, Reclassification of BP; however, these diagnostic definitions do not include pregnant women, and whether newly diagnosed stage 1 hypertension affects pregnancy complications …

18 - 45 years of age Female Phase N/A
S Silvia Giugliano, PhD

A Novel Multiomic AI Approach for Early Preeclampsia Prediction in Pregnancy

Preeclampsia (PE) is a leading cause of maternal-fetal morbidity and mortality, affecting 3-8% of pregnancies and causing over 76,000 maternal deaths annually. PE is characterized by high blood pressure and proteinuria or organ damage/intrauterine growth restriction (IUGR). There are two phenotypes: placental PE, caused by abnormal trophoblast invasion, often leading …

18 years of age Female Phase N/A
Z Zihan Yin, MD

Clinical Characteristics and Prognosis of Acute Stroke in Pregnancy and Puerperium

The objectives of this study are: (1) to describe the detailed clinical characteristics and prognosis of ASPP patients in order to explore the risk factors of ASPP, and to compare the short-term and long-term functional recovery outcomes between them and their controls; (2) to evaluate the risk of recurrent stroke, …

years of age Female Phase N/A

A Study to Assess Pregnancy Outcomes in Women Exposed to Diroximel Fumarate

The primary objective of the study is to estimate the prevalence of major congenital malformations (MCMs) and compare the prevalence between the diroximel fumarate (DRF) and comparator groups. The secondary objectives of the study are to estimate the incidence of spontaneous abortion (SA) and compare the incidence between the DRF …

18 - 49 years of age Female Phase N/A
A Adele Reddin, BSc/MSc

The Impact of E-cigarettes During Pregnancy on Childhood Health Outcomes Study

Tobacco smoking in pregnancy is now widely accepted as having adverse health outcomes for both the mother and fetus. Tobacco smoking in pregnancy is associated with increased incidence of miscarriage, stillbirth and preterm birth as well as low birthweight, respiratory infections, wheeze and asthma in childhood. E-cigarettes are a popular …

18 - 46 years of age Female Phase N/A
M María G Donday, PhD

Safety of IBD Drugs During Pregnancy and Breasfeeding: Mothers and Babies' Outcomes

This is an observational study where pregnant women treated with non-anti-TNF agents or targeted small molecules approved for IBD treatment will be included. Although it is a multicentre, nationwide study, the number of patients to be included is expected to be relatively low (in DUMBO 1, during 5 years of …

18 - 70 years of age Female Phase N/A
M Marta Guerra, MS

Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)

The PROMISSE Study is an observational study of 700 pregnant patients, enrolled at nine major clinical centers. The purpose of the study is 1) to determine whether certain proteins (called complement split products) that can injure healthy organs can be used to predict poor pregnancy outcome in patients with systemic …

18 - 45 years of age Female Phase N/A

Safety of IBD Drugs During Pregnancy and Breastfeeding: Mothers and Babies' Outcomes (DUMBO Registry)

This is a prospective, observational, multicenter registry, which will enrol pregnant women with IBD (CD, UC, or unclassified IBD) over 5 years in Spain. In addition, each incident gestation will be followed-up during pregnancy, and children born to those mothers will be followed-up over 4 years to determine the incidence …

18 years of age Female Phase N/A

Post-Authorization Safety Study for Assessment of Pregnancy Outcomes in Patients Treated With Mayzent

This study will utilize a prospective, observational, exposure cohort design to examine pregnancy and infant outcomes in women and infants who are exposed to siponimod during pregnancy to treat MS.

years of age Female Phase N/A
W Wolfgang Huber-Schneider

Influencing a Vegan Diet and the Intake of Dietary Supplements During Pregnancy and Childhood

The main goals of the exploratory, cross-sectional survey among vegans are to reveal influencing factors, sources of information gathering, reasons for choosing certain dietary supplements of pregnant vegans and parents, difficulties in administering dietary supplements to children, and the compliance of dietary supplements of vegans, because there is no data …

18 years of age All Phase N/A

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