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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 626 clinical trials

Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity

The aim of the NODAL clinical trial is to demonstrate the feasibility of new, low-cost, non-invasive biomarkers of neurodegenerative pathologies as early Alzheimer and Parkinson, based on the estimation of the multimodal connectome.

50 - 80 years of age All Phase N/A
N Nathan DeTurk, MD, MBA

Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait

The purpose of this research is to determine how deep brain stimulation (DBS) for Parkinson's disease affects attention and visuospatial function. Additionally, this study will evaluate how deficits in visual attention are associated with freezing of gait (FOG) in Parkinson's disease. There is currently no reliable treatment for FOG and …

18 years of age All Phase N/A
A Androulla Pillos Smith

Observational Case Series of Patients With Parkinson's Disease (PD) Attending a Complementary Medicine Neuro-degenerative Disease (NDD) Clinic.

When the charity Homeopathy UK launched a new London based charitable clinic for Neurodegenerative Diseases (NDD), including Parkinson's Disease (PD), it was considered important to document patient's experiences of a high-quality complementary medicine clinic, to enable a greater understanding of the role of complementary medicine for PD. Routine clinical data, …

18 years of age All Phase N/A
Y Yunjung Kim, PhD

Dysarthria Management for Minor Groups

This study develops and conduct a small-scale clinical trial study in which the linguistic and cultural diversity of the participants is considered. Speech therapy and counseling services are provided to both patients with Parkinson\'s disease and their caregivers.

25 - 85 years of age All Phase N/A

Early Stage of Alzheimer's and Parkinson's Diseases, HearIng Relevance (SAPHIR)

The study aims to phenotype hearing in patients with early stage of neurodegenerative disorders to explore the prevalence of various hearing disorders in comparison to a control population. Specific focus is made on patients with speech-in-noise intelligibiltiy deficit despite normal tonal audiograms referred to as hidden hearing loss, with potential …

50 - 85 years of age All Phase N/A
E Elvira Maranesi

Innovative Models in the Rehabilitation of the Elderly With Parkinson's Disease Through Technological Innovation

The final goal of the present study is to propose a new approach in the Parkinson's Disease rehabilitation, focused on the use of robotic devices and to check the results not only at the end of the treatment but also in the long term, foreseeing 3 follow-up.

65 years of age All Phase N/A
R Robert Rissmann, PharmD, PhD

Research Into the Safety of a New Agent (VT-5006) in People With and Without Parkinson's Disease

This is a first-in-human (FIH) study of orally administered VT-5006 (also known as AX-5006) in healthy adult volunteers (HVs) and adult participants with Parkinson's disease (PD). The goal of this clinical trial is to learn if VT-5006 is safe and tolerable in healthy volunteers and in participants with PD. It …

18 - 80 years of age All Phase 1
I Isabela L Cavalcante

Effects of Transcranial Direct Current Stimulation Combined With Nordic Walking on Gait and Balance in Parkinson's Disease

Parkinson's disease can cause slow or unsteady walking and balance problems that raise the risk of falls. This study will test whether adding a gentle, non-invasive brain stimulation called transcranial direct current stimulation (tDCS) during a supervised Nordic Walking program improves mobility in people with Parkinson's disease. Participants will be …

50 - 75 years of age All Phase N/A
L Lena Salzmann, PhD student

Investigating Neural Biomarkers for Gait in Parkinson's Patients

This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options. Participants will undergo a protocol that involves walking and gait-related motor tasks, such as seated stepping. During the protocol, brain activity will be recorded.

18 years of age All Phase N/A
M Miguel Angel Fernández del Olmo, PhD

Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease

A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on motor function will be evaluated.

years of age All Phase N/A

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