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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 628 clinical trials
G Gemma Moya-Galé, Ph.D.

Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease

The goal of this clinical trial is to learn whether noise-augmented feedback using automatic speech recognition improves intelligibility and social participation in individuals with Parkinson's disease. The main questions the investigators will address are: Does noise-augmented feedback lead to increased intelligibility, as measured by transcription accuracy scores? Does a self-managed …

50 - 80 years of age All Phase 0
Y Yayun Lee, PhD

Influence of Autonomy on Motor Learning in People With Parkinson's Disease

The goal of this clinical trial is to explore the benefits of autonomy supported learning in patients with Parkinson's disease. The main questions to answer are: Whether autonomy supported learning can benefit motor learning in PD patients Whether autonomy supported learning can enhance intrinsic motivation and/ or information processing of …

20 years of age All Phase N/A
A Ashley Pham

A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease

The purpose of this study is to evaluate the safety, tolerability, and PK/PD of LY3962681 in healthy volunteers and patients with Parkinson's disease. The study will be comprised of two parts, the Single Ascending Dose (SAD) study and the Multiple Ascending Doses (MAD) study. During the SAD portion of the …

30 - 80 years of age All Phase 1
R Ray-Yau Wang, PhD

The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease

A cross-sectional study (part 1) aims to investigate the influence of fatigue on the MI ability in PD compared to healthy controls. A randomized controlled trial (part 2) aims to compare the effect of fNIRS-based NFB-MI on balance and gait performance versus MI only in people with PD.

40 - 85 years of age All Phase N/A
C Chinese PLA General Hospital

VIM+PTT MRgFUS for PD

The objective of this prospective, single-arm, open-label study is to assess the safety and efficacy of the staged, dual-target(VIM+PTT thalamotomy)to treat Patiensts with Parkinson Disease using transcranial magnetic resonance guided focused ultrasound system ExAblate 4000, InSightec Ltd.

22 years of age All Phase N/A
K Kaitlin Lansford, PhD

Listener Training for Improved Intelligibility of People With Parkinson's Disease

Listener training offers a promising avenue for improving communication for people with dysarthria due to Parkinson's disease by offsetting the intelligibility burden from the patient onto their primary communication partners. Here, we employ a repeated-measures, randomized controlled trial to establish the efficacy of listener training for patients with PD and …

18 years of age All Phase N/A

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve …

50 - 80 years of age All Phase N/A

Training of Nursing Home Professionals and Quality of Life of Residents With Parkinson's Disease

The complexity of medication treatments and the diversity of symptoms in Parkinson's disease (PD) require healthcare professionals to have specific knowledge of the disease in order to manage symptoms optimally and on an individualized basis. This becomes even more important as the disease progresses due to the evolution of symptoms …

18 years of age All Phase N/A
G Gemma Lombardi, MD, PhD

A Novel Accessible and Widespread Healthcare Service Model Based on Technology Innovation for Objective (Early) Diagnosis and Therapeutic Monitoring of Parkinson's Disease Promoting Continuity of Care

The present study aims to use the SensMode System - a system composed of wearable devices for upper and lower limb movement analysis and electronic device for data acquisition and processing - on healthy subjects, subjects with idiopathic hyposmia, patients with Parkinson's disease, and subjects with de-novo drug-naïve extrapyramidal syndrome. …

50 - 80 years of age All Phase N/A
A Adam Heredia, EdD

Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease

This research will investigate the safety and usability of the Cionic Neural Sleeve Multistim System for Parkinson's Disease.

22 - 75 years of age All Phase N/A

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