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Obesity Clinical Trials

A listing of Obesity medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,212 clinical trials
M Ma huan, doctor

Weight Loss Via Intelligent Guidance in Patients With Coronary Heart Disease and Obesity: a Randomized Clinical Trial

Coronary Heart Disease (CHD) is an ischemic heart disease caused by coronary atherosclerosis, and it is the leading cause of death from cardiovascular diseases worldwide. Weight loss in obese patients can significantly improve metabolic indicators such as dyslipidemia and insulin resistance; therefore, weight loss may become a target for improving …

18 - 65 years of age All Phase N/A
Z Zhiguang Zhou, Doctor

Phase II Study of THDBH120 Injection in Overweight or Obese Subjects

To assess the efficacy and safety of THDBH120 injection compared with placebo in weight reduction in overweight or obese subjects after 26 weeks of treatment.

18 - 75 years of age All Phase 2
S Stephen Hall

A Study to Evaluate MWN109 Injection in Healthy Subjects

This study is a Phase1, randomized, double-blinded, and placebo-controlled study. In each cohort, enrolled participants will be randomized to receive either placebo or MWN109.

18 - 50 years of age All Phase 1
O Oleksa Rewa, MD

Transpulmonary Assessment for Individualized Lung Optimization in Obese Patients

This protocol describes a randomized controlled feasibility vanguard study designed to investigate the implementation and effects of esophageal pressure-guided positive end-expiratory pressure (PEEP) titration in patients with high body mass index (BMI) mechanically ventilated patients at the Edmonton Zone. The study will enroll 30 patients with body mass index (BMI) …

18 years of age All Phase 2
J Jennifer Smith-Powell, BA

Digital Wellness Nurse - FIT Families: Virtual Family Intervention for Adolescent Obesity

The purpose of the research is to evaluate the digital wellness nurse (DWN) app to find out if it is helpful in delivering the FIT Families intervention. The study is sponsored by the National Institutes of Health (NIH).

12 - 17 years of age All Phase N/A
N Nesreen Baobid

Impact of Beta-glucan Supplementation During Calorie and Carbohydrate-restricted Diet on Body Weight and Body Fat Loss, Appetite, and Gastrointestinal Appetite Hormones.

This study will investigate whether beta-glucan supplementation, when added to an energy and carbohydrate-restricted diet, facilitates body weight and body fat loss, and leads to less detrimental changes in subjective appetite and gastrointestinal appetite hormones. This will be a double-blind, randomised, controlled trial in which healthy females living with overweight …

18 - 60 years of age Female Phase N/A
O Omar Obeid, PhD

The Effect of Oral Iron Supplements on Insulin and Glucose Metabolism in Overweight and Obese Women

The study will be a randomized, double-blind, 17-day metabolic intervention trial including 14 days of high-dose or low-dose iron supplementation. A total of 70 overweight or obese (OW/OB) women will be enrolled. Participants will be individually randomized into either the high-iron or low-iron group. Women in the low-iron group will …

18 - 45 years of age Female Phase N/A

Alveolar Recruitment in Obese Patients in Major Gynaecological Cancer Surgery

In this study, the investigators planned to evaluate the effect of alveolar recruitment strategy primarily on postoperative pulmonary complications in obese patients undergoing lung protective ventilation in major open gynaeco-oncological surgeries. Our other aim was to evaluate perioperative haemodynamics, respiratory mechanics,inpatient length of stay.

18 years of age Female Phase N/A
S Sylvia Santosa, PhD

Acute and Chronic Effects of Obesity

The goal of this study is to understand if there are differences in the fat, muscle and metabolism of individuals who developed obesity during childhood versus those who developed obesity in adulthood. We will do this by having recruited participants undergo subcutaneous adipose tissue biopsies in the abdomen and thigh, …

25 - 40 years of age All Phase N/A
M Mohamed Hantirah, Prof.

Comparison Between Individualized PEEP Ventilation Guided by Driving Pressure and Conventional Lung Protective Strategy in Obese Patients Undergoing Laparoscopic Bariatric Surgery

this study to compare the ventilation in obese patients either using Driving pressure ventilation technique or conventional protective lung strategy all by using Lung ultrasound score

18 - 60 years of age All Phase N/A

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