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Carotid Doppler Changes After Passive Leg Raising for Prediction of Post-Induction Hypotension in Gastrointestinal Tumor Surgery

Carotid Doppler Changes After Passive Leg Raising for Prediction of Post-Induction Hypotension in Gastrointestinal Tumor Surgery

Recruiting
18 years and older
All
Phase N/A

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Overview

This prospective study aims to investigate the role of the passive leg raise maneuver prior to anesthesia induction in predicting post-induction hypotension among elective gastrointestinal tumor surgery patients using carotid artery Doppler parameters.

Description

The study will be conducted on patients scheduled for elective gastrointestinal tumor surgery. Prior to anesthesia induction, a passive leg raise maneuver will be performed. Carotid artery Doppler parameters and hemodynamic changes will be measured and recorded to evaluate their efficacy in predicting subsequent post-induction hypotension.

Eligibility

Inclusion Criteria:

  • Adults aged 18 years or older
  • Patients scheduled for elective gastrointestinal tumor surgery
  • Surgery planned under general anesthesia
  • Body mass index (BMI) \<40 kg/m²
  • Written informed consent provided

Exclusion Criteria:

  • Refusal to participate or inability to obtain written informed consent
  • Body mass index (BMI) ≥40 kg/m²
  • Pregnancy
  • Emergency surgery
  • Difficult intubation
  • ASA physical status ≥IV
  • Pediatric patients (\<18 years)
  • Inability to perform carotid Doppler measurements
  • Arrhythmia other than continuous sinus rhythm or uncontrolled cardiac arrhythmia
  • Severe cardiac dysfunction or left ventricular ejection fraction \<40%
  • Severe valvular heart disease
  • Clinically significant autonomic nervous system disorders
  • Inadequate noninvasive blood pressure monitoring or inability to obtain the required hemodynamic measurements
  • Active sepsis or systemic inflammatory syndrome
  • Severe peripheral vascular disease or significant carotid artery stenosis (\>50%)
  • Severe pulmonary disease or advanced respiratory failure
  • Implanted cardiac device (pacemaker/ICD)
  • Baseline mean arterial pressure (MAP) \<65 mmHg
  • Preoperative systolic blood pressure \>190 mmHg or diastolic blood pressure \>110 mmHg

Study details
    Post-induction Hypotension (PIH)
    Gastrointestinal Tumor Surgery

NCT07777159

Ankara City Hospital Bilkent

31 October 2026

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